Title:
NITROGEN AND SULFUR-CONTAINING HETEROCYCLE DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/2010/025436
Kind Code:
A3
Abstract:
The present invention provides nitrogen and sulfur-containing heterocycle compounds to be used as scaffolds and, in particular, nitrogen and sulfur-containing heterocycle compounds having a thiomorpholine core. The compounds herein described may be useful in treating diseases such as diabetes, obesity, cancer, cardiovascular, Alzheimer's, inflammatory, antidepressant, rheumatoid arthritis, multiple scelerosis, allergic rhinitis, asthma as well as viral and bacterial infections. The compounds herein described may also be useful in treating CNS disorders such as but not limited to Schizophrenia, Alzheimer's disease (AD).
Inventors:
ARMILLI MURTY N (US)
Application Number:
PCT/US2009/055464
Publication Date:
June 17, 2010
Filing Date:
August 29, 2009
Export Citation:
Assignee:
TRIAD MULTITECH PHARMACEUTICAL (US)
ARMILLI MURTY N (US)
ARMILLI MURTY N (US)
International Classes:
C07D401/14; A61K31/381; A61K31/4164; A61K31/517; A61P3/10; A61P19/02; A61P35/00; C07D401/12; C07D403/12; C07D403/14
Domestic Patent References:
| WO2002050091A1 | 2002-06-27 |
Other References:
MICHIO, N. ET AL.: "Thiomorpholine derivatives. II. Reaction of 2- alkyl-3- oxoperhydro-2H-1,4-thiazine-5-carboxylic acids with sulfuryl chloride", YAKUGAKU ZASSHI, vol. 91, no. 2, 1971, pages 166 - 173
KIERAN, F.G. ET AL.: "Cyclization of N-Terminal S-Carbamoylmethylcysteine Causing Loss of 17 Da from peptides and extra peaks in peptide maps", JOURNAL OF PROTEOM RESEARCH, vol. 1, no. 2, 2002, pages 181 - 187
KIERAN, F.G. ET AL.: "Cyclization of N-Terminal S-Carbamoylmethylcysteine Causing Loss of 17 Da from peptides and extra peaks in peptide maps", JOURNAL OF PROTEOM RESEARCH, vol. 1, no. 2, 2002, pages 181 - 187
Attorney, Agent or Firm:
GIBBS, Barbara, S. (111 Monument Circle Suite 270, Indianapolis IN, US)
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