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Title:
NITROXYALKYLAMIDE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/1993/009085
Kind Code:
A1
Abstract:
Constitution: a nitroxyalkylamide derivative represented by the general formula (I): R1-(A)n-COHN-B-ONO2, wherein R1 represents optionally substituted heterocyclic, heterocyclic oxy, aryloxy or arylthio; A represents C1-C4 alkylene; B represents C1-C4 alkylene; and n represents 0 or 1. Effect: this compound is excellent in collateral vasodilatory and antianginal activities and hence is useful as a remedy for angina pectoris.

Inventors:
ISHIHARA SADAO (JP)
SAITO FUJIO (JP)
KATAOKA MITSURU (JP)
KOIKE HIROYUKI (JP)
MIYAKE SHIGEKI (JP)
MIZUNO HIROSHI (JP)
Application Number:
PCT/JP1992/001419
Publication Date:
May 13, 1993
Filing Date:
November 02, 1992
Export Citation:
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Assignee:
SANKYO CO (JP)
International Classes:
A61K31/27; A61K31/34; A61K31/341; A61K31/38; A61K31/381; A61K31/41; A61P9/08; A61P9/10; C07C233/08; C07C233/13; C07C235/20; A61K31/16; C07C235/22; C07C271/48; C07C323/60; C07C323/62; C07C333/04; C07D261/08; C07D261/10; C07D261/12; C07D307/54; C07D307/68; C07D307/71; C07D319/20; C07D333/38; (IPC1-7): A61K31/16; A61K31/34; A61K31/38; A61K31/41; C07C235/22; C07D261/08; C07D261/12; C07D307/54; C07D307/58; C07D333/22; C07D333/24
Foreign References:
JPS63233962A1988-09-29
JPS61148151A1986-07-05
Other References:
See also references of EP 0641768A4
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