Title:
NON-AQUEOUS COMPOSITION HAVING DRUG CARRIED THEREIN, AND METHOD FOR PRODUCING SAME
Document Type and Number:
WIPO Patent Application WO/2018/182039
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing: a non-aqueous composition having a drug carried therein, which can be prepared by mixing a drug-containing fat emulsion that can be used as an injectable solution, an eye drop, a nasal spray, an inhalant and the like with an aqueous medium upon use without needing to produce a drug-containing fat emulsion in advance; and a method for producing the non-aqueous composition. The non-aqueous composition having a drug carried therein according to the present invention, which is a solution for the problem, is characterized in that components are dissolved in a polyhydric alcohol that serves as a water-soluble carrier in such a manner that the content of an oil or fat can be 0.05 to 250 mg/g, the ratio of the content of a poorly-water-soluble drug to the content of the oil or fat (i.e., (poorly-water-soluble drug)/(oil or fat)) can be 0.0001 to 50 by weight (provided that the total content of the poorly-water-soluble drug and the oil or fat is up to 300 mg/g) and the content of an emulsifying agent can be 20 to 500 mg/g.
More Like This:
Inventors:
NABETA KIICHIRO (JP)
Application Number:
PCT/JP2018/014030
Publication Date:
October 04, 2018
Filing Date:
March 31, 2018
Export Citation:
Assignee:
TECHNO GUARD CO LTD (JP)
International Classes:
A61K47/44; A61K9/08; A61K31/337; A61K31/5575; A61K31/573; A61K47/10
Foreign References:
| JP2010270023A | 2010-12-02 | |||
| JP2013536805A | 2013-09-26 | |||
| JP2013209347A | 2013-10-10 | |||
| JPH04164024A | 1992-06-09 | |||
| JPH10504291A | 1998-04-28 |
Attorney, Agent or Firm:
TSUJITA Takashi et al. (JP)
Download PDF: