Title:
NON-AQUEOUS PATCH
Document Type and Number:
WIPO Patent Application WO/2013/046335
Kind Code:
A1
Abstract:
[Problem] In a non-aqueous patch containing lidocaine, the adhesive force of the preparation tends to lower with an increase in the content of lidocaine. To release an effective amount of lidocaine from a patch to the skin, it is a common practice to dissolve lidocaine using a solubilizing agent. However, an increase in the content of the solubilizing agent causes even more remarkable lowering of the adhesive force, which makes long-term adhesion impossible. [Solution] A non-aqueous patch, wherein a biaxially stretching extensible fabric having a strength under 50% extension in the long side direction of not more than 2000 g/50 mm is used as a support for a lidocaine-containing ointment, and an ointment base contains a solubilizing agent together with lidocaine and/or a reaction product thereof.
Inventors:
MORI TASUYA (JP)
SAIDA NAOYUKI (JP)
SAIDA NAOYUKI (JP)
Application Number:
PCT/JP2011/072072
Publication Date:
April 04, 2013
Filing Date:
September 27, 2011
Export Citation:
Assignee:
ITOCHU CHEMICAL FRONTIER CORP (JP)
OISHI KOSEIDO CO LTD (JP)
MORI TASUYA (JP)
SAIDA NAOYUKI (JP)
OISHI KOSEIDO CO LTD (JP)
MORI TASUYA (JP)
SAIDA NAOYUKI (JP)
International Classes:
A61K31/167; A61K9/70; A61K47/10; A61K47/12; A61L15/00; A61P21/00; A61P23/02
Domestic Patent References:
| WO1992015289A1 | 1992-09-17 | |||
| WO2010016219A1 | 2010-02-11 | |||
| WO2009060629A1 | 2009-05-14 |
Foreign References:
| EP1238664A1 | 2002-09-11 | |||
| EP2210599A1 | 2010-07-28 | |||
| JP2001302501A | 2001-10-31 | |||
| JP3159688B2 | 2001-04-23 | |||
| JPH07215850A | 1995-08-15 | |||
| JPH09315964A | 1997-12-09 | |||
| JP2001302501A | 2001-10-31 | |||
| JP2816765B2 | 1998-10-27 |
Other References:
See also references of EP 2823815A4
Attorney, Agent or Firm:
KANAKURA Kyoji (JP)
Kanekura Takashi 2 (JP)
Kanekura Takashi 2 (JP)
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Claims: