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Patent Searching and Data


Title:
NON-INVASIVE FETAL RHD GENOTYPING FROM MATERNAL WHOLE BLOOD
Document Type and Number:
WIPO Patent Application WO/2010/009440
Kind Code:
A3
Abstract:
The present invention discloses methods of determining the RhD genotype of subject. In particular, the invention provides a non-invasive method of determining fetal RhD genotype from a maternal biological sample containing fetal cells. The invention also provides novel probes and primers useful in the described methods. Kits and mixtures comprising the novel probes and primers are also disclosed.

Inventors:
FAN WEN-HUA (US)
TIM ROGER (US)
KOSCO KARENA (US)
BHATT RAM (US)
Application Number:
PCT/US2009/051061
Publication Date:
May 20, 2010
Filing Date:
July 17, 2009
Export Citation:
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Assignee:
BIOCEPT INC (US)
FAN WEN-HUA (US)
TIM ROGER (US)
KOSCO KARENA (US)
BHATT RAM (US)
International Classes:
C07K19/00; C12Q1/68; G01N33/50
Foreign References:
US5723293A1998-03-03
US20080071076A12008-03-20
US4683195A1987-07-28
Other References:
YOUNG REE KIM ET AL.: "RHD Genotyping in RhD-negative Korean Donors -by Polymerase Chain Reaction-Sequence Specific Primers (PCR-SSP) Method", KOREAN J CLIN PATHOL., vol. 20, 2000, pages 92 - 97, XP008142742
Attorney, Agent or Firm:
FOX, George et al. (777 6th Street NW,Suite 110, Washington DC, US)
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