Title:
NOVEL 2-ACYLAMINOTHIAZOLE DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/045907
Kind Code:
A1
Abstract:
The present invention relates to a novel 2-acylaminothiazole derivative. The present invention also relates to a method for preparing the novel 2-acylaminothiazole derivatives and intermediates thereof, as well as to a pharmaceutical composition comprising the compounds. In addition, the present invention also relates to the use of the novel 2-acylaminothiazole derivatives and the pharmaceutical composition comprising same in the treatment and/or prevention of thrombopoietin receptor-mediated diseases.
Inventors:
CAI JIAQIANG (CN)
YU NAN (CN)
ZENG HONG (CN)
SONG HONGMEI (CN)
QING YAN (CN)
SONG SHUAI (CN)
DENG HANWEN (CN)
TANG ZUJIAN (CN)
DUAN XIAOFAN (CN)
HUANG HAITAO (CN)
YE HONG (CN)
LIU GANG (CN)
WANG LICHUN (CN)
WANG JINGYI (CN)
YU NAN (CN)
ZENG HONG (CN)
SONG HONGMEI (CN)
QING YAN (CN)
SONG SHUAI (CN)
DENG HANWEN (CN)
TANG ZUJIAN (CN)
DUAN XIAOFAN (CN)
HUANG HAITAO (CN)
YE HONG (CN)
LIU GANG (CN)
WANG LICHUN (CN)
WANG JINGYI (CN)
Application Number:
PCT/CN2017/099945
Publication Date:
March 15, 2018
Filing Date:
August 31, 2017
Export Citation:
Assignee:
SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN)
International Classes:
C07D487/04; A61K31/4545; A61P7/02; C07D471/04; C07D471/08; C07D487/08; C07D487/10
Domestic Patent References:
| WO2007004038A1 | 2007-01-11 | |||
| WO2005014561A1 | 2005-02-17 | |||
| WO2007004038A1 | 2007-01-11 | |||
| WO2009017098A1 | 2009-02-05 |
Foreign References:
| CN101809008A | 2010-08-18 |
Other References:
See also references of EP 3511332A4
BAZAN, PROC. NATL. ACAD. SCI. USA, vol. 87, 1990, pages 6934 - 6938
SOUYRI ET AL., CELL, vol. 63, 1990, pages 1137 - 1147
METHIA ET AL., BLOOD, vol. 82, 1993, pages 1395 - 1401
HARKER, J. CLIN. INVEST., vol. 47, 1968, pages 458 - 465
METCALF, NATURE, vol. 369, 1994, pages 519 - 520
HARKER ET AL., BLOOD, vol. 91, 1996, pages 4427 - 4433
ALI ET AL., BLOOD COAGULATION & FIBRINOLYSIS, vol. 27, no. 1, 2016, pages 4 - 52
BAZAN, PROC. NATL. ACAD. SCI. USA, vol. 87, 1990, pages 6934 - 6938
SOUYRI ET AL., CELL, vol. 63, 1990, pages 1137 - 1147
METHIA ET AL., BLOOD, vol. 82, 1993, pages 1395 - 1401
HARKER, J. CLIN. INVEST., vol. 47, 1968, pages 458 - 465
METCALF, NATURE, vol. 369, 1994, pages 519 - 520
HARKER ET AL., BLOOD, vol. 91, 1996, pages 4427 - 4433
ALI ET AL., BLOOD COAGULATION & FIBRINOLYSIS, vol. 27, no. 1, 2016, pages 4 - 52
Attorney, Agent or Firm:
CHINA PATENT AGENT (H.K.) LTD. (CN)
Download PDF: