Title:
NOVEL ACETHYLENE AMIDE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2015/046317
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide novel acethylene amide derivatives, i.e., a compound having an antagonistic activity on all of PPARα, PPARβ/δ and PPARγ, a compound having an antagonistic activity on at least one subtype among PPARα, PPARβ/δ and PPARγ, and a compound capable of inhibiting a PPARγ-selective antagonistic activity. A compound provided by the present invention is an acethylene amide derivative represented by general formula (I).
Inventors:
MIYACHI HIROYUKI (JP)
OOHASHI MASAO (JP)
OOHASHI MASAO (JP)
Application Number:
PCT/JP2014/075403
Publication Date:
April 02, 2015
Filing Date:
September 25, 2014
Export Citation:
Assignee:
UNIV OKAYAMA NAT UNIV CORP (JP)
International Classes:
C07C233/78; A61K31/167; A61K31/381; A61K31/44; A61K31/505; A61K31/506; A61P3/04; A61P3/10; A61P17/00; A61P19/08; A61P31/14; A61P35/00; A61P43/00; C07C231/14; C07C235/50; C07C237/34; C07D211/06; C07D239/26; C07D333/24; C07D401/12; C07D409/12
Domestic Patent References:
| WO2001092201A1 | 2001-12-06 | |||
| WO2000075103A1 | 2000-12-14 | |||
| WO2001025181A1 | 2001-04-12 | |||
| WO2002044131A1 | 2002-06-06 |
Foreign References:
| JP2010539199A | 2010-12-16 |
Other References:
DATABASE REGISTRY 31 August 2009 (2009-08-31), accession no. 178447-63-6
Attorney, Agent or Firm:
OKUHARA Koji et al. (JP)
Yasushi Okuhara (JP)
Yasushi Okuhara (JP)
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