NOVEL ALKALINE PROTEASE VARIANTS AND DETERGENTS AND CLEANSERS CONTAINING THESE NOVEL ALKALINE PROTEASE VARIANTS

Title:

NOVEL ALKALINE PROTEASE VARIANTS AND DETERGENTS AND CLEANSERS CONTAINING THESE NOVEL ALKALINE PROTEASE VARIANTS

Document Type and Number:

WIPO Patent Application WO2003038082

Kind Code:

A3

Abstract:

The invention relates to novel alkaline protease variants. These variants have, when enumerating the alkaline protease from Bacillus lentus, variations in amino acid position 61, positions 199 and/or 211 and, optionally, at least one modification that contributes to the stabilization of the molecule, said modification preferably being point mutations in positions 3 and/or 4. Particularly preferred are variants S3T/V4l/G61A/V199l and S3T/V4l/G61A/V199l/L211D of B. lentus alkaline protease. The invention also relates to the possible uses of these enzymes in diverse technical processes and, in particular, to detergents and cleansers containing these novel alkaline protease variants.

Inventors:

KOTTWITZ BEATRIX (DE)
MAURER KARL-HEINZ (DE)
BREVES ROLAND (DE)

Application Number:

PCT/EP2002/011725

Publication Date:

September 18, 2003

Filing Date:

October 19, 2002

Export Citation:

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Assignee:

HENKEL KGAA (DE)
KOTTWITZ BEATRIX (DE)
MAURER KARL-HEINZ (DE)
BREVES ROLAND (DE)

International Classes:

A23C19/032; A23L1/00; A61K8/00; A61K8/66; A23K1/165; A61K8/72; A61Q19/10; C11D3/386; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/54; C12N15/09; C12N15/57; C12P21/06; C12Q1/37; C14C11/00; D06L4/40; D06M16/00; D06M101/12; (IPC1-7): C12N9/54; C11D3/386; C12N15/57; A61K7/28

Domestic Patent References:

WO1996028566A2	1996-09-19
WO1995030010A1	1995-11-09
WO1995023221A1	1995-08-31

Foreign References:

CA2049097A1

1992-02-16

Other References: