Title:
NOVEL AMIDE AND AMIDINE DERIVATIVES AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2010/123838
Kind Code:
A3
Abstract:
The present invention relates to inhibitors of 11- β-hydroxysteroid dehydrogenase type 1 enzyme and their use in treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, central nervous system disorders, and diseases and conditions that are related to excessive glucocorticoids.
Inventors:
PEDDI SRIDHAR (US)
PATEL MEENA V (US)
ROHDE JEFFREY J (US)
PATEL MEENA V (US)
ROHDE JEFFREY J (US)
Application Number:
PCT/US2010/031660
Publication Date:
March 03, 2011
Filing Date:
April 20, 2010
Export Citation:
Assignee:
ABBOTT LAB (US)
PEDDI SRIDHAR (US)
PATEL MEENA V (US)
ROHDE JEFFREY J (US)
PEDDI SRIDHAR (US)
PATEL MEENA V (US)
ROHDE JEFFREY J (US)
International Classes:
C07C261/04; A61K31/26; A61P3/10; A61P25/00; C07C257/14
Domestic Patent References:
WO2006024628A1 | 2006-03-09 |
Foreign References:
EP0333522A2 | 1989-09-20 | |||
EP0418065A2 | 1991-03-20 | |||
US20060149070A1 | 2006-07-06 | |||
US5338745A | 1994-08-16 |
Attorney, Agent or Firm:
VEPACHEDU, Sreenivasarao et al. (Dept. 0377 Bldg. AP6A-1A,100 Abbott Park Roa, Abbott Park Illinois, US)
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