Title:
NOVEL AMINOGLYCOSIDE ANTIBIOTIC EFFECTIVE AGAINST MULTIDRUG-RESISTANT BACTERIA
Document Type and Number:
WIPO Patent Application WO/2017/018528
Kind Code:
A1
Abstract:
Disclosed are: a compound represented by general formula (I), or a pharmaceutically acceptable salt of the compound, or a solvate of the compound or the pharmaceutically acceptable salt; a pharmaceutical composition containing the compound, the pharmaceutically acceptable salt or the solvate; a use of the compound, the pharmaceutically acceptable salt or the solvate for the prevention or treatment of infectious diseases; and a method for preventing or treating infectious diseases using the compound, the pharmaceutically acceptable salt or the solvate. The compound represented by general formula (I) has an antibacterial activity against both gram-positive bacteria and gram-negative bacteria, and is therefore useful for the prevention or treatment of infectious diseases induced by these bacteria.
Inventors:
TAKAHASHI YOSHIAKI (JP)
UMEMURA EIJIRO (JP)
IDA TAKASHI (JP)
IGARASHI MASAYUKI (JP)
UMEMURA EIJIRO (JP)
IDA TAKASHI (JP)
IGARASHI MASAYUKI (JP)
Application Number:
PCT/JP2016/072400
Publication Date:
February 02, 2017
Filing Date:
July 29, 2016
Export Citation:
Assignee:
MICROBIAL CHEM RES FOUND (JP)
MEIJI SEIKA PHARMA CO LTD (JP)
MEIJI SEIKA PHARMA CO LTD (JP)
International Classes:
C07H15/12; A61K31/7036; A61P31/04; C07H15/234
Domestic Patent References:
| WO2013191550A1 | 2013-12-27 |
Foreign References:
| JP2013537177A | 2013-09-30 | |||
| US4379917A | 1983-04-12 | |||
| US4360665A | 1982-11-23 | |||
| JPS5772998A | 1982-05-07 | |||
| JPS5772999A | 1982-05-07 | |||
| US4458065A | 1984-07-03 | |||
| JPS5782398A | 1982-05-22 | |||
| JPS5782399A | 1982-05-22 |
Other References:
DOBUTSUYO IYAKU HYOKASHO APRAMYCIN, July 2013 (2013-07-01), pages 1 - 33, XP009504054
INTRODUCTION TO MODERN PHARMACEUTICS, 10 April 1987 (1987-04-10), pages 273 - 274, XP009504060
MODERN PHARMACEUTICS, 15 December 2011 (2011-12-15), pages 381 - 386, XP009504053
DATABASE Registry [o] 13 November 2009 (2009-11-13), XP055458373, retrieved from STN Database accession no. 1192350-04-1
INTRODUCTION TO MODERN PHARMACEUTICS, 10 April 1987 (1987-04-10), pages 273 - 274, XP009504060
MODERN PHARMACEUTICS, 15 December 2011 (2011-12-15), pages 381 - 386, XP009504053
DATABASE Registry [o] 13 November 2009 (2009-11-13), XP055458373, retrieved from STN Database accession no. 1192350-04-1
Attorney, Agent or Firm:
NAGAI Hiroshi et al. (JP)
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