NOVEL ANTI-CD3 ANTIBODIES AND USES THEREOF

WIPO Patent Application WO/2023/169419

A1

Provided are anti-CD3 antibodies or antigen-binding fragments thereof, isolated polynucleotides encoding the same, pharmaceutical composition comprising the same and the uses thereof.

WO/2020/172189	BISPECIFIC FUSION PROTEIN USING ORTHOPOXVIRUS MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) CLASS l-LIKE PROTEIN (OMCP) AND TUMOR-SPECIFIC BINDING PARTNER
WO/2007/007160	ANTI-MADCAM ANTIBODIES TO TREAT FEVER
JP2002516069	[Title of Invention] TNF-related death ligand

YUWEN HUI (CN)
REN YIJING (CN)
LI TENGTENG (CN)
CHEN PENG (CN)
HOU BING (CN)
SHAN BO (CN)
MEI JAY (CN)

PCT/CN2023/080090

September 14, 2023

March 07, 2023

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ANTENGENE HANGZHOU BIOLOGICS CO LTD (CN)
ANTENGENE BIOLOGICS LTD (CN)

C07K16/28; A61P35/00; C12N5/20; C12N15/85; G01N33/577

CN110799538A	2020-02-14
CN1984931A	2007-06-20
US20180273622A1	2018-09-27
US20200115449A1	2020-04-16
US20190359712A1	2019-11-28

ZHANG, NAN; CHEN, MING JIE; CHEN, JING ET AL.: "Cloning and sequence analysis of VH and VL gene of anti-CD3 McAb", ZHONGGUO MIANYIXUE ZAZHI = CHINESE JOURNAL OF IMMUNOLOGY, JILIN SHENG YIXUE QIKANSHE, CN, vol. 18, no. 9, 25 September 2002 (2002-09-25), CN , pages 608 - 610, XP009548959, ISSN: 1000-484X
WERNLY BERNHARD, PAAR VERA, AIGNER ACHIM, PILZ PATRICK M, PODESSER BRUNO K, FÖRSTER MARTIN, JUNG CHRISTIAN, PINON HOFBAUER JOSEFIN: "Anti-CD3 Antibody Treatment Reduces Scar Formation in a Rat Model of Myocardial Infarction", CELLS, vol. 9, no. 2, pages 295, XP093090935, DOI: 10.3390/cells9020295

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