Title:
NOVEL ANTI-HUMAN OX40 LIGAND ANTIBODY, AND ANTI-INFLUENZA DRUG COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO/2016/002820
Kind Code:
A1
Abstract:
The problem to be solved by the present invention is to provide a drug which can treat influenza by such a novel mechanism that the drug can prevent the adhesion of influenza viruses onto the surfaces of cells. The present invention provides an anti-human OX40L antibody capable of binding specifically to a domain containing an asparagine residue located at position-90 in human OX40L.
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Inventors:
KIKUCHI TOSHIAKI (JP)
HIRANO TAIZOU (JP)
ICHINOSE MASAKAZU (JP)
ISHII NAOTO (JP)
TANAKA YUETSU (JP)
HIRANO TAIZOU (JP)
ICHINOSE MASAKAZU (JP)
ISHII NAOTO (JP)
TANAKA YUETSU (JP)
Application Number:
PCT/JP2015/068920
Publication Date:
January 07, 2016
Filing Date:
June 30, 2015
Export Citation:
Assignee:
UNIV TOHOKU (JP)
UNIV RYUKYUS (JP)
UNIV RYUKYUS (JP)
International Classes:
C07K16/28; A61K39/395; A61P31/16; A61P43/00; C07K14/705; G01N33/15; G01N33/50; C12N15/09; C12P21/08
Foreign References:
| JP2006506041A | 2006-02-23 | |||
| JP2009519718A | 2009-05-21 | |||
| JP2008512995A | 2008-05-01 | |||
| JP2007530045A | 2007-11-01 |
Other References:
WANG, Q. ET AL.: "Characterization and functional study of five novel monoclonal antibodies against human OX40L highlight reverse signalling: enhancement of IgG production of B cells and promotion of maturation of DCs.", TISSUE ANTIGENS, vol. 64, no. 5, November 2004 (2004-11-01), pages 566 - 574, XP002360583
CROFT, M.: "Control of immunity by the TNFR- related molecule OX40 ( CD 134).", ANNU. REV. IMMUNOL., vol. 28, 2010, pages 57 - 78, XP055039398
CROFT, M.: "Control of immunity by the TNFR- related molecule OX40 ( CD 134).", ANNU. REV. IMMUNOL., vol. 28, 2010, pages 57 - 78, XP055039398
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
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