Title:
NOVEL ANTIBODIES AND METHODS OF USE FOR THE TREATMENT AND DIAGNOSIS OF CANCER
Document Type and Number:
WIPO Patent Application WO/2011/145085
Kind Code:
A3
Abstract:
The present invention is related to monoclonal antibodies, fragments, antigen binding portions or fragments thereof, for specific binding to human and/or mouse tumor associated carbohydrate antigens expressed on cancer cells, e.g., human colorectal adenocarcinma, non-small cell lung carcinoma (NSCLC). These antibodies can be used to induce selective cell death in cancer cells and for the treatment of cancer, e.g., NSCLC and/or in the diagnosis of cancers expressing tumor associated carbohydrate antigens in-vitro and in-vivo.
Inventors:
BENHAR ITAI (IL)
YAKIR YESHAYAHU (IL)
YAKIR YESHAYAHU (IL)
Application Number:
PCT/IB2011/052228
Publication Date:
March 01, 2012
Filing Date:
May 22, 2011
Export Citation:
Assignee:
PROCOGNIA ISRAEL LTD (IL)
BENHAR ITAI (IL)
YAKIR YESHAYAHU (IL)
UNIV RAMOT (IL)
BENHAR ITAI (IL)
YAKIR YESHAYAHU (IL)
UNIV RAMOT (IL)
International Classes:
C07K16/30; G01N33/574
Domestic Patent References:
| WO2009028580A1 | 2009-03-05 | |||
| WO2008153237A1 | 2008-12-18 | |||
| WO2010050528A1 | 2010-05-06 |
Attorney, Agent or Firm:
DR. D. GRAESER LTD et al. (POB 2496, Raanana, IL)
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