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Title:
NOVEL ANTIBODIES
Document Type and Number:
WIPO Patent Application WO/2017/079369
Kind Code:
A3
Abstract:
Disclosed in this invention are human IgG Fc variants sequences that demonstrate low and no binding activities to Fc gamma receptor. The disclosed Fc variants are useful for making Fc fusion proteins and/or IgGs where low or no Fc effector function of the mentioned molecules are desirable.

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Inventors:
ZHOU HONGXING (US)
Application Number:
PCT/US2016/060227
Publication Date:
June 15, 2017
Filing Date:
November 03, 2016
Export Citation:
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Assignee:
GLAXOSMITHKLINE LLC (US)
International Classes:
C07K16/00; C07K16/18; C07K16/42
Domestic Patent References:
WO2005047327A22005-05-26
Foreign References:
US5834597A1998-11-10
US20150125458A12015-05-07
US20150110810A12015-04-23
US20060057701A12006-03-16
Attorney, Agent or Firm:
HAN, William, T. et al. (US)
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