Title:
NOVEL ARTERIOSCLEROSIS TREATMENT DRUG COMPOSITION AND METHOD FOR SCREENING ARTERIOSCLEROSIS TREATMENT DRUGS
Document Type and Number:
WIPO Patent Application WO/2013/154128
Kind Code:
A1
Abstract:
The present invention pertains to: the use as the target of treatment for dyslipidemia, hyperlipidemia, arteriosclerosis, or Alzheimer's disease of a gene coding for the human CTNNB1, human NFE2L2, human TXN, human CUL1, human RAE1, human TNFRSF10C, human BCLAF1, human TNIP1, human STK38, human ZC3H13, human C14orf122, human C4orf18, human ARS2, human C4orf20, human RC74, human EP400, human RUFY1, human EPPK1, human SLA2, human FTMT, human GPR139, human OR10AG1, human C1QTNF9, human UBE2NL, human FLJ16734 or human FLJ38596 proteins; a treatment agent for dyslipidemia, hyperlipidemia, arteriosclerosis, or Alzheimer's disease targeting the genes; and a method for screening treatment agents for dyslipidemia, hyperlipidemia, arteriosclerosis, or Alzheimer's disease targeting the genes.
Inventors:
YAMAGUCHI YOKO (JP)
ROKUSHIMA MASATOMO (JP)
YAMAMOTO SHIGENORI (JP)
ITOH TAKESHI (JP)
MAEKAWA KAZUHIKO (JP)
ROKUSHIMA MASATOMO (JP)
YAMAMOTO SHIGENORI (JP)
ITOH TAKESHI (JP)
MAEKAWA KAZUHIKO (JP)
Application Number:
PCT/JP2013/060798
Publication Date:
October 17, 2013
Filing Date:
April 10, 2013
Export Citation:
Assignee:
SHIONOGI & CO (JP)
International Classes:
A61K45/00; A61K31/7088; A61K31/7105; A61K35/76; A61K48/00; A61P3/06; A61P9/10; A61P25/28; C12N15/113; C12Q1/02; C12Q1/68; G01N33/15; G01N33/50
Domestic Patent References:
| WO2008109460A2 | 2008-09-12 | |||
| WO2012018754A2 | 2012-02-09 |
Foreign References:
| JP2008535474A | 2008-09-04 | |||
| JP2006522831A | 2006-10-05 |
Attorney, Agent or Firm:
TAKAYAMA, Hirotsugu et al. (JP)
Hiromitsu Takayama (JP)
Hiromitsu Takayama (JP)
Download PDF: