Title:
NOVEL BENZOXAZINE DERIVATIVE, MEDICINE CONTAINING THE SAME, AND INTERMEDIATE THEREFOR
Document Type and Number:
WIPO Patent Application WO/1994/018195
Kind Code:
A1
Abstract:
A benzoxazine derivative useful as a potassium channel activator and represented by general formula (I), a pharmaceutically acceptable salt thereof, a stereo-chemical isomer thereof, a medicinal composition containing the same, another benzoxazine derivative useful as an intermediate for the production thereof and represented by general formula (II), and a salt thereof. In formula (I), R1 represents hydrogen, lower alkyl, lower alkanoyl, carbamoyl, mono- or di(lower alkyl)carbamoyl or nitro; R2 represents lower alkyl; R3 represents nitro; m represents an integer of 1 to 4; and n represents 0 or 1. In formula (II), R1, R2, R3 and m are each as defined above.
Inventors:
MATSUMOTO YUZO (JP)
UCHIDA WATARU (JP)
YANAGISAWA ISAO (JP)
UCHIDA WATARU (JP)
YANAGISAWA ISAO (JP)
Application Number:
PCT/JP1994/000174
Publication Date:
August 18, 1994
Filing Date:
February 04, 1994
Export Citation:
Assignee:
YAMANOUCHI PHARMA CO LTD (JP)
MATSUMOTO YUZO (JP)
UCHIDA WATARU (JP)
YANAGISAWA ISAO (JP)
MATSUMOTO YUZO (JP)
UCHIDA WATARU (JP)
YANAGISAWA ISAO (JP)
International Classes:
C07D265/36; C07D413/04; (IPC1-7): C07D413/04; A61K31/535; C07D265/36
Foreign References:
| JPH04178375A | 1992-06-25 | |||
| EP0488008A1 | 1992-06-03 |
Download PDF: