Title:
NOVEL BIFIDOBACTERIUM BACTERIA AND COMPOSITION INCLUDING NOVEL BIFIDOBACTERIUM BACTERIA
Document Type and Number:
WIPO Patent Application WO/2019/112053
Kind Code:
A1
Abstract:
The present invention provides: good bacteria that can be used beneficially across a wide range of age groups; and a composition that includes the good bacteria. Bifidobacterium longum subspecies longum NITE BP-02564 and/or Bifidobacterium longum subspecies longum NITE BP-02565; bacteria that are classified as Bifidobacterium longum subspecies longum that can utilize sialic acid; and a composition that includes the abovementioned bacteria. More preferably, a composition that includes sialic acid. More preferably, a composition that includes: at least one type of carbohydrate selected from the group that consists of arabinoxylan, arabinan, pectic galactan, and oligosaccharides derived from arabinoxylan, arabinan, and pectic galactan; or at least a carbohydrate derived from a Gramineae plant or a carbohydrate derived from a Solanaceae plant.
Inventors:
ODAMAKI TOSHITAKA (JP)
KATO KUMIKO (JP)
KATO KUMIKO (JP)
Application Number:
PCT/JP2018/045166
Publication Date:
June 13, 2019
Filing Date:
December 07, 2018
Export Citation:
Assignee:
MORINAGA MILK INDUSTRY CO LTD (JP)
International Classes:
C12N1/20; A23L33/135; A61K36/06; A61P25/00; A61P31/00; A61P37/00; A61P37/02
Domestic Patent References:
| WO2016175702A1 | 2016-11-03 |
Foreign References:
| EP3181683A1 | 2017-06-21 | |||
| JP2014094001A | 2014-05-22 |
Other References:
YU ZHUO-TENG ET AL.: "Utilization of major fucosylated and sialylated human milk oligosaccharides by isolated human gut microbes", GLYCOBIOLOGY, vol. 23, no. 11, September 2013 (2013-09-01), pages 1281 - 1292, XP055487446, doi:10.1093/glycob/cwt065
LEE H. ET AL.: "Hydrolysis of milk gangliosides by infant-gut associated bifidobacteria determined by microfluidic chips and high-resolution mass spectrometry", ELECTROPHORESIS, vol. 35, no. 11, June 2014 (2014-06-01), pages 1742 - 1750, XP055616506
RIVIERE A. ET AL.: "The Ability of Bifidobacteria To Degrade Arabinoxylan Oligosaccharide Constituents and Derived Oligosaccharides Is Strain Dependent", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 80, no. 1, 2014, pages 204 - 217, XP055276012, doi:10.1128/AEM.02853-13
GAVLIGHI H. A. ET AL.: "Enzymatic Depolymerization of Gum Tragacanth: Bifidogenic Potential of Low Molecular Weight Oligosaccharides", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol. 61, 2013, pages 1272 - 1278, XP055176861, doi:10.1021/jf304795f
SAKURAMA H. ET AL.: "Lacto-N-biosidase Encoded by a Novel Gene of Bifidobacterium longum Subspecies longum Shows Unique Substrate Specificity and Requires a Designated Chaperone for Its Active Expression", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 288, no. 35, 30 August 2013 (2013-08-30), pages 25194 - 25206, XP055616508
NATURE COMMUNICATIONS, vol. 7, no. 11939, 2016, pages 1 - 12
NATURE COMMUNICATIONS, vol. 80, no. 14, 2014
"Biological significance of human milk oligosaccharides", MILK SCIENCE, vol. 56, no. 4, 2008, pages 155 - 176
HEALTH PROMOTION ACT, 31 August 2009 (2009-08-31)
See also references of EP 3722413A4
LEE H. ET AL.: "Hydrolysis of milk gangliosides by infant-gut associated bifidobacteria determined by microfluidic chips and high-resolution mass spectrometry", ELECTROPHORESIS, vol. 35, no. 11, June 2014 (2014-06-01), pages 1742 - 1750, XP055616506
RIVIERE A. ET AL.: "The Ability of Bifidobacteria To Degrade Arabinoxylan Oligosaccharide Constituents and Derived Oligosaccharides Is Strain Dependent", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 80, no. 1, 2014, pages 204 - 217, XP055276012, doi:10.1128/AEM.02853-13
GAVLIGHI H. A. ET AL.: "Enzymatic Depolymerization of Gum Tragacanth: Bifidogenic Potential of Low Molecular Weight Oligosaccharides", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol. 61, 2013, pages 1272 - 1278, XP055176861, doi:10.1021/jf304795f
SAKURAMA H. ET AL.: "Lacto-N-biosidase Encoded by a Novel Gene of Bifidobacterium longum Subspecies longum Shows Unique Substrate Specificity and Requires a Designated Chaperone for Its Active Expression", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 288, no. 35, 30 August 2013 (2013-08-30), pages 25194 - 25206, XP055616508
NATURE COMMUNICATIONS, vol. 7, no. 11939, 2016, pages 1 - 12
NATURE COMMUNICATIONS, vol. 80, no. 14, 2014
"Biological significance of human milk oligosaccharides", MILK SCIENCE, vol. 56, no. 4, 2008, pages 155 - 176
HEALTH PROMOTION ACT, 31 August 2009 (2009-08-31)
See also references of EP 3722413A4
Attorney, Agent or Firm:
WATANABE Kaoru (JP)
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