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Patent Searching and Data


Title:
NOVEL BORIC ACID DERIVATIVE AND PHARMACEUTICAL COMPOSITION USING SAME
Document Type and Number:
WIPO Patent Application WO/2018/133661
Kind Code:
A1
Abstract:
The present invention discloses a novel boric acid derivative and a pharmaceutical composition using the same, pertaining to the field of medicinal chemistry. The boric acid derivative is a compound represented by formula (I). The present invention further provides a use of the boric acid derivative in the preparation of an antitumor drug or a proteasome inhibitor drug. Specifically, the present invention provides a use of the boric acid derivative in the preparation of a proteasome chymotrypsin-like protease inhibitor drug, and a use in drugs for the prophylaxis and/or treatment of cancer such as multiple myeloma and colon cancer, providing a new choice for clinical screening and/or preparation of proteasome inhibitor drugs and drugs for cancer such as multiple myeloma and colon cancer, having wide application prospects.

Inventors:
GUANG BING (CN)
YANG TAI (CN)
DONG RENHAN (CN)
LIU JIN (CN)
Application Number:
PCT/CN2018/000027
Publication Date:
July 26, 2018
Filing Date:
January 23, 2018
Export Citation:
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Assignee:
CHENGDU ORIGIN BIOTECHNOLOGY LTD COMPANY (CN)
International Classes:
C07F5/02; A61K31/69; A61P35/00; C07F5/04
Foreign References:
CN103435638A2013-12-11
CN102603781A2012-07-25
Attorney, Agent or Firm:
GAOYUNG INTELLECTUAL PROPERTY AGENCY (CN)
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