Title:
NOVEL BRASSINOSTEROID ANALOGUE, NOVEL CRYSTALLINE FORM AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/115741
Kind Code:
A1
Abstract:
Disclosed in the present invention are a novel brassinosteroid analogue, a novel crystalline form and a preparation method therefor and an application thereof. The chemical formula of the brassinosteroid analogue is C27H46O7, the chemical name of the brassinosteroid analogue is (20R,22R)-2β,3β,14α-14,20,22,25-hexahydroxy-5β,8α,9α-cholest-6-ketone, and the structural formula is shown as aa. According to the present invention, by improving the recrystallization process of a naturally extracted brassinosteroid analogue, the novel crystalline form having high biological activity can be obtained, and the novel crystalline form can be applied to the field of agriculture to promote plant growth.
Inventors:
HE QIMING (CN)
REN DAN (CN)
REN DAN (CN)
Application Number:
PCT/CN2022/083659
Publication Date:
June 29, 2023
Filing Date:
March 29, 2022
Export Citation:
Assignee:
CHENGDU NEWSUN CROP SCIENCE CO LTD (CN)
International Classes:
C07J9/00; A01N45/00; A01P21/00
Foreign References:
| CN114276400A | 2022-04-05 | |||
| CN103282373A | 2013-09-04 | |||
| RU2434877C1 | 2011-11-27 | |||
| CN109221132A | 2019-01-18 | |||
| CN110839645A | 2020-02-28 | |||
| CN103214546A | 2013-07-24 |
Other References:
THUSSAGUNPANIT JUTIPORN, JUTAMANEE KANAPOL, KAVEETA LILY, CHAI-ARREE WITITH, PANKEAN PORN, HOMVISASEVONGSA SUREEPORN, SUKSAMRARN A: "Comparative Effects of Brassinosteroid and Brassinosteroid Mimic on Improving Photosynthesis, Lipid Peroxidation, and Rice Seed Set under Heat Stress", JOURNAL OF PLANT GROWTH REGULATION., SPRINGER VERLAG, NEW YORK, NY., US, vol. 34, no. 2, 1 June 2015 (2015-06-01), US , pages 320 - 331, XP093074354, ISSN: 0721-7595, DOI: 10.1007/s00344-014-9467-4
ODINOKOV V. N., AFON’KINA S. R., SHAFIKOV R. V., SAVCHENKO R. G., GALYAUTDINOV I. V., KHALILOV L. M., SHASHKOV A. S.: "7,8-dihydro analogs of ecdysteroids", RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, M A I K NAUKA - INTERPERIODICA, RU, vol. 43, no. 6, 1 June 2007 (2007-06-01), RU , pages 825 - 833, XP093074358, ISSN: 1070-4280, DOI: 10.1134/S107042800706005X
SUKSAMRARN, APICHART ET AL.: "Stereoselective Catalytic Hydrogenation of Δ7-6-Ketosteroids in the Presence of Sodium Nitrite", TETRAHEDRON, vol. 58, no. 30, 31 December 2002 (2002-12-31), XP004379332, ISSN: 0040-4020, DOI: 10.1016/S0040-4020(02)00580-X
ODINOKOV V. N., AFON’KINA S. R., SHAFIKOV R. V., SAVCHENKO R. G., GALYAUTDINOV I. V., KHALILOV L. M., SHASHKOV A. S.: "7,8-dihydro analogs of ecdysteroids", RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, M A I K NAUKA - INTERPERIODICA, RU, vol. 43, no. 6, 1 June 2007 (2007-06-01), RU , pages 825 - 833, XP093074358, ISSN: 1070-4280, DOI: 10.1134/S107042800706005X
SUKSAMRARN, APICHART ET AL.: "Stereoselective Catalytic Hydrogenation of Δ7-6-Ketosteroids in the Presence of Sodium Nitrite", TETRAHEDRON, vol. 58, no. 30, 31 December 2002 (2002-12-31), XP004379332, ISSN: 0040-4020, DOI: 10.1016/S0040-4020(02)00580-X
Attorney, Agent or Firm:
CHENGDU XINGZHI ZHIXIN INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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