NOVEL CAROTENOID-RELATED DERIVATIVES, AND SALTS, ESTERS, OR AMIDES THEREOF

WIPO Patent Application WO/2020/027304

A1

Provided are carotenoid derivatives having exceptional hydrophilicity and oral absorptivity. A carotenoid-related compound represented by the formula (in the formula, X represents a carbonyl group or a methylene group, and Z1 and Z2 are the same or different and represent a group selected from (a), (b), (c), and (d) below: (a) a hydroxy group (however, Z1 and Z2 are not simultaneously hydroxy groups); (b) -OR1 (R1 represents an optionally substituted hydrocarbon group or the like); (c) -SR2 (R2 represents an optionally substituted hydrocarbon group or the like); (d) -NR3R4 (R3 represents a hydrogen atom, an optionally substituted hydrocarbon group, or the like, R4 represents a hydrogen atom, an optionally substituted hydrocarbon group, or the like, and R3 and R4 may form a heterocycle together with nitrogen atoms)), pharmacologically acceptable salts thereof, or pharmacologically acceptable esters or amides thereof.

WO/2002/060865	PROCESS OF OBTAINING HIGH PURITY OF ZEAXANTHIN, CRYPTOXANTHIN & OTHER CAROTENOIDS FROM BYADAGI CHILI/CHAPPATTA CHILI & CAROTENOID COMPOSITION
WO/2002/050022	PROCESS FOR THE PRODUCTION OF CAROTENOIDS
WO/1986/004059	METHOD FOR EXTRACTING CAROTENE FROM CARROTS AND CAROTENE CONCENTRATE THUS OBTAINED

YOKOYAMA TOMIHISA (JP)
NISHIDA YASUHIRO (JP)
OGAWA MAKOTO (JP)
YAMANO KATSUHIRO (JP)
FUJITA TAKASHI (JP)
MORIIZUMI KIYOTAKA (JP)
SHINOHARA RYOMA (JP)
KOBAYASHI SATOSHI (JP)
SAKATA RYO (JP)
FUKUYAMA KEI (JP)
NAKAZAWA KENTA (JP)
IWANO YUJI (JP)

PCT/JP2019/030382

February 06, 2020

August 01, 2019

Click for automatic bibliography generation  

ASTA PHARMACEUTICALS CO LTD (JP)

C07C403/24; A61K31/015; A61K31/122; A61K31/13; A61K31/133; A61K31/136; A61K31/19; A61K31/194; A61K31/215; A61K31/275; A61K31/395; A61K31/40; A61K31/403; A61K31/4178; A61K31/427; A61K31/438; A61K31/444; A61K31/4545; A61K31/496; A61K31/5355; A61K31/541; A61K31/55; A61K31/551; A61K31/655; A61P37/02; A61P39/06; A61P43/00; C07D207/16; C07D209/44; C07D211/14; C07D211/44; C07D211/58; C07D211/62; C07D213/36; C07D213/73; C07D223/04; C07D233/61; C07D243/08; C07D257/04; C07D277/04; C07D295/116; C07D295/15; C07D519/00

WO2005102356A1	2005-11-03
WO2006105214A2	2006-10-05
WO2015178404A1	2015-11-26

JP2006517197A

2006-07-20

INANAGA, JUNJI ET AL.: "Transformation of zeaxanthin into 3,3'-diamino- and dimercapto-beta -carotene derivatives", MEMOIRS OF THE FACULTY OF SCIENCE, vol. 17, no. 1, 1989, pages 109 - 112
BAI, AIPING ET AL.: "All-trans retioic acid down- regulates inflammatory responses by shifting the Treg/Th17 profile in human ulcerative and murine colitis", J. LEUK. BIOL., vol. 86, 2009, pages 959 - 969, XP055683612
KAWASHIMA, TADAOMI: "A marine carotenoid, Fucoxanthin, induces regulatory T cells and inhibits Th17 cell differentiation in vitro", BIOSCI. BIOTECHNOL. BIOCHEM., vol. 75, no. 10, 2011, pages 2066 - 2069

THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)

View/Download PDF      PDF Help

Previous Patent: INFORMATION PROCESSING DEVICE, INFORMATION PROCESSING METHOD, AND PROGRAM

Next Patent: DEVICE AND METHOD FOR CONTROLLING BRAIN WAVES AND CELL ACTIVITY BY PHOTIC STIMULATION, AND DEVICE FO...