Title:
NOVEL CEPHEM DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/1996/037499
Kind Code:
A1
Abstract:
Compounds represented by general formula (I) and having a 'beta'-(optionally substituted imidazo[5,1-b]thiazolyl)vinyl group at the 3-position of the cephem ring, and salts and esters thereof. These compounds have an extremely broad antimicrobial spectrum and exerts potent antimicrobial effects on Gram-positive bacteria, Gram-negative bacteria and even resistant bacteria. In formula (I) X represents CH or N; R1 represents hydrogen or an amino protecting group; R2 represents hydrogen, C1-6 alkyl, C3-7 cycloalkyl or a hydroxy protecting group; R3 is not present or represents hydrogen, a cation forming a salt or a carboxy protecting group; R4, R5 and R6 may be the same or different and each represents hydrogen or C1-6 alkyl; R7+ is not present or represents a cation of C1-6 alkyl; and n is an integer of 0 or 1.
More Like This:
| JPH01102082 | CEPHEM COMPOUND |
| JPH0789968 | NOVEL CEPHEM COMPOUND |
| JPS5762283 | BETA-LACTAM COMPOUND CONTAINING SULFUR OR SELENIUM |
Inventors:
UMEMURA EIJIRO (JP)
ATSUMI KUNIO (JP)
IWAMATSU KATSUYOSHI (JP)
TAMURA ATSUSHI (JP)
ATSUMI KUNIO (JP)
IWAMATSU KATSUYOSHI (JP)
TAMURA ATSUSHI (JP)
Application Number:
PCT/JP1996/001406
Publication Date:
November 28, 1996
Filing Date:
May 24, 1996
Export Citation:
Assignee:
MEIJI SEIKA CO (JP)
UMEMURA EIJIRO (JP)
ATSUMI KUNIO (JP)
IWAMATSU KATSUYOSHI (JP)
TAMURA ATSUSHI (JP)
UMEMURA EIJIRO (JP)
ATSUMI KUNIO (JP)
IWAMATSU KATSUYOSHI (JP)
TAMURA ATSUSHI (JP)
International Classes:
A61K31/545; A61P31/04; C07D501/00; C07D501/56; C07D519/06; (IPC1-7): C07D519/00; A61K31/545
Domestic Patent References:
| WO1996005205A1 | 1996-02-22 |
Foreign References:
| JPH01261391A | 1989-10-18 |
Other References:
See also references of EP 0774466A4
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