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Title:
NOVEL CINNAMIC ACID RELATED COMPOUNDS
Document Type and Number:
WIPO Patent Application WO/2006/011669
Kind Code:
A1
Abstract:
Novel cinnamic acid-related compounds and salts thereof which are useful as drugs, specifically, compounds represented by the general formula [1] and salts thereof: [1] wherein A is a six-membered hydrocarbon ring or a six-membered heterocycle; Ra1 is H, alkyl, or aryl; Ra2 is H, halogeno, OH, or the like; Ra3 is H, halogeno, OH, alkoxy, or the like; Ra4 is carboxy, amino, or the like; Xa is -C(=N-Ra5)-, -CRa6Ra7-, -NRa8-, or the like; Ra5 is H, OH, alkoxy, or the like; Ra6 and Ra7 are each H, halogeno, or the like; Ra6 and Ra7 may form a cyclohexane ring; Ra8 is H, OH, alkoxy, or the like; Ya is alkylene, -O-alkylene, or the like; and the broken line represents a single or double bond.

Inventors:
TAJIMA HISASHI (JP)
MORI TOSHIYUKI (JP)
MATSUBAYASHI KENICHIRO (JP)
SUHARA HIROSHI (JP)
KIRIHARA TOMOKO (JP)
SHIMAZAKI ATSUSHI (JP)
Application Number:
PCT/JP2005/014262
Publication Date:
February 02, 2006
Filing Date:
July 28, 2005
Export Citation:
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Assignee:
SANTEN PHARMA CO LTD (JP)
TAJIMA HISASHI (JP)
MORI TOSHIYUKI (JP)
MATSUBAYASHI KENICHIRO (JP)
SUHARA HIROSHI (JP)
KIRIHARA TOMOKO (JP)
SHIMAZAKI ATSUSHI (JP)
International Classes:
C07C59/88; A61K31/192; A61K31/216; A61K31/382; A61K31/445; A61K31/495; A61K31/5375; A61P27/06; C07C59/125; C07C59/48; C07C59/64; C07C59/84; C07C69/734; C07C69/738; C07C233/65; C07C251/48; C07C317/44; C07D211/34; C07D213/75; C07D295/10; C07D301/12; C07D303/22; C07D303/32; C07D311/36; C07D335/06
Foreign References:
JPH07258074A1995-10-09
JP2000256259A2000-09-19
JPH10509987A1998-09-29
US3501503A1970-03-17
US4342782A1982-08-03
US5506226A1996-04-09
JP2000063340A2000-02-29
JPH11514015A1999-11-30
JP2001139550A2001-05-22
JP2000336063A2000-12-05
Attorney, Agent or Firm:
Hibi, Norihiko c/o KISHIMOTO & CO. (3rd Floor Inaba Building, 13-18, Nishishinsaibashi 1-chome, Chuo-k, Osaka-shi Osaka, JP)
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