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Title:
NOVEL COMPOUND OF 4'-THIONUCLEOSIDE, AS WELL AS PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/155593
Kind Code:
A1
Abstract:
The present invention relates to a novel compound of 4'-thionucleoside, a preparation method therefor, a pharmaceutical composition comprising the same and an application thereof. Specifically, the present invention relates to a phosphamide derivative of 4'-thionucleoside, a preparation method therefor, a pharmaceutical composition comprising the same, a use thereof in the preparation of a medicine for preventing or treating abnormal cell proliferation diseases (for example, tumors or cancers and related diseases) or virus infectious diseases, and a method of using the same for preventing or treating abnormal cell proliferation diseases (for example, tumors or cancers and related diseases) or virus infectious diseases.

Inventors:
YE, Hong (No.666, Xinhua Avenue Hai Xia Industrial Park, Wenjiang Distric, Chengdu Sichuan 8, 611138, CN)
LIU, Gang (No.666, Xinhua Avenue Hai Xia Industrial Park, Wenjiang Distric, Chengdu Sichuan 8, 611138, CN)
YU, Nan (No.666, Xinhua Avenue Hai Xia Industrial Park, Wenjiang Distric, Chengdu Sichuan 8, 611138, CN)
ZENG, Hong (No.666, Xinhua Avenue Hai Xia Industrial Park, Wenjiang Distric, Chengdu Sichuan 8, 611138, CN)
ZHAO, Mingliang (No.666, Xinhua Avenue Hai Xia Industrial Park, Wenjiang Distric, Chengdu Sichuan 8, 611138, CN)
QING, Yan (No.666, Xinhua Avenue Hai Xia Industrial Park, Wenjiang Distric, Chengdu Sichuan 8, 611138, CN)
DENG, Hua (No.666, Xinhua Avenue Hai Xia Industrial Park, Wenjiang Distric, Chengdu Sichuan 8, 611138, CN)
LI, Wenjia (No.666, Xinhua Avenue Hai Xia Industrial Park, Wenjiang Distric, Chengdu Sichuan 8, 611138, CN)
LI, Donghong (No.666, Xinhua Avenue Hai Xia Industrial Park, Wenjiang Distric, Chengdu Sichuan 8, 611138, CN)
SU, Donghai (No.666, Xinhua Avenue Hai Xia Industrial Park, Wenjiang Distric, Chengdu Sichuan 8, 611138, CN)
ZHONG, Wei (No.666, Xinhua Avenue Hai Xia Industrial Park, Wenjiang Distric, Chengdu Sichuan 8, 611138, CN)
LI, Shaohua (No.666, Xinhua Avenue Hai Xia Industrial Park, Wenjiang Distric, Chengdu Sichuan 8, 611138, CN)
WU, Xunwei (No.666, Xinhua Avenue Hai Xia Industrial Park, Wenjiang Distric, Chengdu Sichuan 8, 611138, CN)
WANG, Lichun (No.666, Xinhua Avenue Hai Xia Industrial Park, Wenjiang Distric, Chengdu Sichuan 8, 611138, CN)
WANG, Jingyi (No.666, Xinhua Avenue Hai Xia Industrial Park, Wenjiang Distric, Chengdu Sichuan 8, 611138, CN)
Application Number:
CN2016/077519
Publication Date:
October 06, 2016
Filing Date:
March 28, 2016
Export Citation:
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Assignee:
SICHUAN KELUN PHARMACEUTICAL RESEARCH INSTITUTE CO. LTD. (No.666, Xinhua Avenue Hai Xia Industrial Park, Wenjiang Distric, Chengdu Sichuan 8, 611138, CN)
International Classes:
C07H19/10; A61K31/7068; A61K31/7076; A61P35/00; A61P35/02; C07H1/00; C07H19/20
Domestic Patent References:
WO2014197578A12014-12-11
Foreign References:
US6147058A2000-11-14
Attorney, Agent or Firm:
NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD. (Room 1802, 18th Floor Block A,Investment Plaza, 27 Jinrongdajie, Xicheng District, Beijing 3, 100033, CN)
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