Title:
NOVEL COMPOUND HAVING BLT INHIBITORY ACTIVITY AND COMPOSITION, FOR PREVENTING OR TREATING INFLAMMATORY DISEASES, COMPRISING SAME AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2017/018750
Kind Code:
A1
Abstract:
The present invention relates to a novel compound showing leukotriene B4 receptor 2 (BLT2) inhibitory activity and a pharmaceutical composition, for preventing or treating inflammatory diseases, comprising same as an active ingredient. In the present invention, a novel compound showing BLT2 inhibitory activity is investigated and the enhanced cancer cell death, metastasis suppression, chemotaxis inhibition, antiasthmatic effect and the like shown in the compound have been experimentally confirmed. Therefore, the present invention enables more fundamental approach and target treatment for treating or preventing inflammatory diseases.
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| JPS61236755 | ALKANOYL ANILIDE |
Inventors:
CHOI YONGSEOK (KR)
KIM JAE-HONG (KR)
LEE KYEONG (KR)
HAN HYO-KYUNG (KR)
WEI JUN DONG (KR)
KWON JINSUN (KR)
GOO JA-IL (KR)
KIM JAE-HONG (KR)
LEE KYEONG (KR)
HAN HYO-KYUNG (KR)
WEI JUN DONG (KR)
KWON JINSUN (KR)
GOO JA-IL (KR)
Application Number:
PCT/KR2016/008069
Publication Date:
February 02, 2017
Filing Date:
July 23, 2016
Export Citation:
Assignee:
DONGGUK UNIV INDUSTRY-ACADEMIC COOP FOUND (KR)
UNIV KOREA RES & BUS FOUND (KR)
UNIV KOREA RES & BUS FOUND (KR)
International Classes:
C07C233/07; A61K31/435; A61K31/4965; A61K31/5375; C07D211/06; C07D241/04; C07D265/30
Domestic Patent References:
| WO2002040466A2 | 2002-05-23 |
Foreign References:
| CN104045552A | 2014-09-17 | |||
| US20060264415A1 | 2006-11-23 | |||
| KR20130017073A | 2013-02-19 | |||
| KR20150080428A | 2015-07-09 |
Other References:
See also references of EP 3327000A4
Attorney, Agent or Firm:
LEE, Myoung-Jin (KR)
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