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Title:
NOVEL COMPOUND HAVING HSP90 INHIBITORY ACTIVITY OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND MEDICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/131500
Kind Code:
A1
Abstract:
The present invention relates to: a novel compound having an HSP90 inhibitory activity or a pharmaceutically acceptable salt thereof; and a medical use thereof. A composition, of the present invention, containing a dihydroxyphenyl-based compound or a benzamide-based compound, which is the novel compound having HSP90 inhibitory activity, can effectively inhibit HSP90, and thus could be useful as a pharmaceutical composition for preventing or treating any one HSP90-mediated disease selected from the group consisting of cancer, degenerative neurological disorders and viral infections, or as a dietary supplement for preventing or alleviating HSP90-mediated diseases.

Inventors:
SEO YOUNG HO (KR)
Application Number:
PCT/KR2017/001034
Publication Date:
August 03, 2017
Filing Date:
January 31, 2017
Export Citation:
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Assignee:
UNIV KEIMYUNG IND ACAD COOP FOUND (KR)
International Classes:
C07C233/64; A23L33/10; A61K31/166; C07B55/00; C07D241/04
Domestic Patent References:
WO2006109075A22006-10-19
WO2006117669A12006-11-09
WO2011154708A12011-12-15
Foreign References:
US20070265268A12007-11-15
Other References:
BARRETT, T. N.: "Synthesis of C-5-substituted resorcylates and resorcinamides via formylation-aromatization of functionalized keto -dioxinones", TETRAHEDRON, 2014, pages 6894 - 6901, XP029044194, DOI: doi:10.1016/j.tet.2014.06.099
Attorney, Agent or Firm:
TAEBAEK INTELLECTUAL PROPERTY LAW FIRM (KR)
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