Title:
NOVEL COMPOUND FOR IMPROVING SLEEP OR USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/121429
Kind Code:
A1
Abstract:
The present invention relates to a novel compound which can provide a sleep improving effect or the use thereof. Some compounds have an adenosine receptor agonistic activity. The novel compound of the present invention can shorten sleep latency and extend total sleep duration, and thus may be effectively used for a pharmaceutical composition for preventing or treating a sleep disorder, a health functional food composition for preventing or relieving a sleep disorder, a composition for improving sleep, a sleep adjuvant, or a method for treating a sleep disorder.
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Inventors:
JUNG YI-SOOK (KR)
KIM EUN HA (KR)
LEE SUNGHOU (KR)
JEE HYE JIN (KR)
PARK JU YOUNG (KR)
KIM EUN HA (KR)
LEE SUNGHOU (KR)
JEE HYE JIN (KR)
PARK JU YOUNG (KR)
Application Number:
PCT/KR2022/021333
Publication Date:
June 29, 2023
Filing Date:
December 26, 2022
Export Citation:
Assignee:
UNIV AJOU IND ACADEMIC COOP FOUND (KR)
SANGMYUNG UNIV CHEONAN COUNCIL FOR INDUSTRY ACADEMIC COOPERATION FOUNDATION (KR)
SANGMYUNG UNIV CHEONAN COUNCIL FOR INDUSTRY ACADEMIC COOPERATION FOUNDATION (KR)
International Classes:
A61K31/517; A61P25/20; C07D239/95; C07D403/04; C07D405/12; C07D405/14
Domestic Patent References:
| WO1997020823A2 | 1997-06-12 |
Foreign References:
| US20090048278A1 | 2009-02-19 |
Other References:
VAN HORN KURT S., BURDA WHITTNEY N., FLEEMAN RENEE, SHAW LINDSEY N., MANETSCH ROMAN: "Antibacterial Activity of a Series of N 2 , N 4 -Disubstituted Quinazoline-2,4-diamines", JOURNAL OF MEDICINAL CHEMISTRY, vol. 57, no. 7, 10 April 2014 (2014-04-10), US , pages 3075 - 3093, XP093074322, ISSN: 0022-2623, DOI: 10.1021/jm500039e
ARNOUT R. D. VOET, AKIHIRO ITO, MIKAKO HIROHAMA, SEIJI MATSUOKA, NAOYA TOCHIO, TAKANORI KIGAWA, MINORU YOSHIDA, KAM Y. J. ZHANG: "Discovery of small molecule inhibitors targeting the SUMO–SIM interaction using a protein interface consensus approach", MEDCHEMCOMM, vol. 5, no. 6, 1 January 2014 (2014-01-01), United Kingdom , pages 783 - 786, XP055293256, ISSN: 2040-2503, DOI: 10.1039/c3md00391d
DATABASE Registry 27 January 2014 (2014-01-27), ANONYMOUS : "2,4-Quinazolinediamine, N2-ethyl-N4,N4-dimethyl- (CA INDEX NAME)", XP093074515, retrieved from STN Database accession no. 1531465-84-5
ARNOUT R. D. VOET, AKIHIRO ITO, MIKAKO HIROHAMA, SEIJI MATSUOKA, NAOYA TOCHIO, TAKANORI KIGAWA, MINORU YOSHIDA, KAM Y. J. ZHANG: "Discovery of small molecule inhibitors targeting the SUMO–SIM interaction using a protein interface consensus approach", MEDCHEMCOMM, vol. 5, no. 6, 1 January 2014 (2014-01-01), United Kingdom , pages 783 - 786, XP055293256, ISSN: 2040-2503, DOI: 10.1039/c3md00391d
DATABASE Registry 27 January 2014 (2014-01-27), ANONYMOUS : "2,4-Quinazolinediamine, N2-ethyl-N4,N4-dimethyl- (CA INDEX NAME)", XP093074515, retrieved from STN Database accession no. 1531465-84-5
Attorney, Agent or Firm:
ERUUM & LEEON INTELLECTUAL PROPERTY LAW FIRM (KR)
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