Title:
NOVEL COMPOUND ISOLATED FROM QUAMOCLIT, AND COMPOSITION FOR PREVENTING OR TREATING DIABETES CONTAINING THE COMPOUND AS AN ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2013/024968
Kind Code:
A1
Abstract:
The present invention relates to a novel compound isolated from quamoclit, and to a composition containing the compound as an active ingredient, and more particularly, to a novel compound isolated from quamoclit, and to a composition for preventing or treating diabetes or diabetic complications containing the compound as an active ingredient. The novel compound derived from quamoclit according to the present invention has superior effects of reducing blood glucose levels, promoting insulin secretion, inhibiting VEGF expression, etc., and thus is effective in preventing or treating diabetes and various diabetic complications and further promotes treatment effects when administered in combination with conventional diabetes treatment agents.
Inventors:
CHUNG BONG HYUN (KR)
YI SO YOEN (KR)
LEE UI JIN (KR)
YI SO YOEN (KR)
LEE UI JIN (KR)
Application Number:
PCT/KR2012/005129
Publication Date:
February 21, 2013
Filing Date:
June 28, 2012
Export Citation:
Assignee:
KOREA RES INST OF BIOSCIENCE (KR)
CHUNG BONG HYUN (KR)
YI SO YOEN (KR)
LEE UI JIN (KR)
CHUNG BONG HYUN (KR)
YI SO YOEN (KR)
LEE UI JIN (KR)
International Classes:
C07D407/14; A23L33/00; A61K31/351; A61K36/39; A61P3/10; C07D407/12
Foreign References:
| KR20080032127A | 2008-04-14 | |||
| KR100988510B1 | 2010-10-20 |
Other References:
See also references of EP 2746280A4
DEFRONZO RA ET AL., DIABETES CARE, vol. 15, 1992, pages 318
VINSON, J.A. ET AL., J. NUTRITINAL BIOCHEMISTRY, vol. 7, 1996, pages 559
SMITH, P. R. ET AL., EUR. J. BIOCHEM., vol. 210, 1992, pages 729
BROWNLEE, M. ET AL., SCIENCES, vol. 232, 1986, pages 1629
YOKOZAWA,T. ET AL., J. OF TRAD. MED., vol. 18, 2001, pages 107
BROWNLEE, M. ET AL., N. ENGL. MED., vol. 318, 1988, pages 1315
AIELLO ET AL., NEW ENGL. J. MED, vol. 331, 1994, pages 1480
PEER ET AL., LAB. INVEST., vol. 72, 1995, pages 638
LOPEZ ET AL., INVEST. OPTHTHALMOL. VIS. SCI., vol. 37, 1996, pages 855
DEFRONZO RA ET AL., DIABETES CARE, vol. 15, 1992, pages 318
VINSON, J.A. ET AL., J. NUTRITINAL BIOCHEMISTRY, vol. 7, 1996, pages 559
SMITH, P. R. ET AL., EUR. J. BIOCHEM., vol. 210, 1992, pages 729
BROWNLEE, M. ET AL., SCIENCES, vol. 232, 1986, pages 1629
YOKOZAWA,T. ET AL., J. OF TRAD. MED., vol. 18, 2001, pages 107
BROWNLEE, M. ET AL., N. ENGL. MED., vol. 318, 1988, pages 1315
AIELLO ET AL., NEW ENGL. J. MED, vol. 331, 1994, pages 1480
PEER ET AL., LAB. INVEST., vol. 72, 1995, pages 638
LOPEZ ET AL., INVEST. OPTHTHALMOL. VIS. SCI., vol. 37, 1996, pages 855
Attorney, Agent or Firm:
LEE, Cheo Young (KR)
이처영 (KR)
이처영 (KR)
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Claims: