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Patent Searching and Data


Title:
NOVEL COMPOUNDS AND METHODS FOR INHIBITING P53 ACTIVITY
Document Type and Number:
WIPO Patent Application WO2007084625
Kind Code:
A9
Abstract:
The present invention features compounds and pharmaceutical compositions comprising the same that are useful for modulating p53 activity. The invention further provides methods for inhibiting the biological activity of p53 and for treating diseases such as, for instance, cancer, cell death caused all or in part by cancer treatments such as chemotherapy or radiation thereapy, neuron cell death, stroke, Alzheimer's Disease and Parkinson's Disease.

Inventors:
ZHOU MING-MING (US)
SACHCHIDANAND D PHIL (US)
ZENG LEI (US)
MANFREDI JAMES J (US)
RESNICK-SILVERMAN LOIS (US)
AARONSON STUART (US)
Application Number:
PCT/US2007/001350
Publication Date:
September 13, 2007
Filing Date:
January 19, 2007
Export Citation:
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Assignee:
SINAI SCHOOL MEDICINE (US)
ZHOU MING-MING (US)
SACHCHIDANAND D PHIL (US)
ZENG LEI (US)
MANFREDI JAMES J (US)
RESNICK-SILVERMAN LOIS (US)
AARONSON STUART (US)
International Classes:
A61K31/473; A61K31/403
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