Title:
NOVEL COMPOUNDS
Document Type and Number:
WIPO Patent Application WO2003051277
Kind Code:
A3
Abstract:
The present invention relates to new compounds of formula (I) wherein R<1>, R<2>, R<3>, R<4>, R<5> and A are defined as in formula (I), a process for their preparation and new intermediate prepared therein, pharmaceutical compositions containing said therapeutically active compounds and to the use of said active compounds in therapy, especially in the treatment of c-Jun N-terminal kinase (JNK) mediated conditions in mammals, particularly Alzheimer's Disease.
Inventors:
KING SARAH (GB)
TEAGUE SIMON (GB)
XUE YAFENG (SE)
SWAHN BRITT-MARIE (SE)
TEAGUE SIMON (GB)
XUE YAFENG (SE)
SWAHN BRITT-MARIE (SE)
Application Number:
PCT/SE2002/002374
Publication Date:
October 30, 2003
Filing Date:
December 18, 2002
Export Citation:
Assignee:
ASTRAZENECA AB (SE)
KING SARAH (GB)
TEAGUE SIMON (GB)
XUE YAFENG (SE)
SWAHN BRITT-MARIE (SE)
KING SARAH (GB)
TEAGUE SIMON (GB)
XUE YAFENG (SE)
SWAHN BRITT-MARIE (SE)
International Classes:
A61K31/4184; A61K31/454; A61K31/4709; A61K31/496; A61P1/02; A61P1/04; A61P1/16; A61P1/18; A61P3/10; A61P5/14; A61P7/00; A61P7/02; A61P7/04; A61P7/06; A61P7/10; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P17/02; A61P17/06; A61P19/00; A61P19/02; A61P19/10; A61P21/00; A61P21/04; A61P25/00; A61P25/06; A61P25/08; A61P25/14; A61P25/16; A61P25/28; A61P27/02; A61P29/00; A61P29/02; A61P31/04; A61P31/12; A61P31/14; A61P31/18; A61P31/20; A61P35/00; A61P35/02; A61P35/04; A61P37/02; A61P37/04; A61P37/06; A61P37/08; A61P43/00; C07D235/26; C07D235/28; C07D401/12; C07D401/14; C07D403/12; C07D403/14; C07D405/14; (IPC1-7): C07D403/12; A61K31/4184; C07D401/12; C07D405/14
Domestic Patent References:
| WO1987005021A1 | 1987-08-27 |
Foreign References:
| EP0220053A2 | 1987-04-29 | |||
| US5814646A | 1998-09-29 |
Other References:
AKERKAR A.S. ET AL.: "Antimycobacterial activity of some quinolyl aryl sulfides, sulfones and ethers, in vitro", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 1, no. 5, pages 392 - 396, XP002964954
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