Title:
NOVEL CRYSTAL FORM OF 3-(4-(BENZYLOXY)PHENYL)HEX-4-INOIC ACID DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2020/242252
Kind Code:
A1
Abstract:
The present invention relates to a novel crystal form of a 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative, a production method therefor and a pharmaceutical composition comprising same. A crystal form I of a compound of chemical formula 1, according to the present invention, exhibits more excellent physicochemical properties such as thermal stability, static electricity-inducing capability, compressibility, etc. compared to an amorphous form or a crystal form II, and thus is especially useful for preparation and long-term storage.
Inventors:
HWANG JEONG UN (KR)
KIM JIN WOONG (KR)
LEE KYU HWAN (KR)
KIM EUN YOUNG (KR)
CHOI SU KYOUNG (KR)
KIM JIN WOONG (KR)
LEE KYU HWAN (KR)
KIM EUN YOUNG (KR)
CHOI SU KYOUNG (KR)
Application Number:
PCT/KR2020/007018
Publication Date:
December 03, 2020
Filing Date:
May 29, 2020
Export Citation:
Assignee:
HYUNDAI PHARM CO LTD (KR)
International Classes:
C07D317/72; A61K31/357; A61P3/00
Domestic Patent References:
| WO2014171762A1 | 2014-10-23 |
Foreign References:
| KR20160046306A | 2016-04-28 | |||
| KR20150126368A | 2015-11-11 | |||
| KR20140126248A | 2014-10-30 | |||
| KR20060093564A | 2006-08-25 |
Other References:
MORRISON, HENRY AND JONA JONAN, WALKER SHAWN D., WOO JACQUELINE C. S., LI LAN, FANG JAN: "Development of a suitable salt form for a GPR40 receptor agonist", ORGANIC PROCESS RESEARCH & DEVELOPMENT, vol. 15, no. 1, 2011, pages 104 - 111, XP055764749, DOI: 10.1021/op100204u
See also references of EP 3978485A4
See also references of EP 3978485A4
Attorney, Agent or Firm:
DANA PATENT LAW FIRM (KR)
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