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Patent Searching and Data


Title:
NOVEL CRYSTALLINE FORM OF DEXTRAL OXIRACETAM, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/076782
Kind Code:
A1
Abstract:
The present invention provides a crystalline form of dextral oxiracetam. The crystalline form has a diffraction peak when a diffraction angle, 2θ, is 17.12±0.2°, 18.88±0.2°,19.24±0.2°, 21.18±0.2°, or 24.88±0.2°. The crystalline form having oxiracetam can promote synthesis of phosphorylcholine and phosphoethanolamine, boosts cerebral metabolism, has a stimulating function on a specific central nervous pathway by means of a blood-brain barrier, improves the intelligence and memory, has an obvious effect on a memory dysfunction, and has special biological activity in the field of sedation and the antiepileptic field. The method for preparing the crystalline form is simple and is suitable for industrial production.

Inventors:
YE LEI (CN)
Application Number:
PCT/CN2017/092219
Publication Date:
May 03, 2018
Filing Date:
July 07, 2017
Export Citation:
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Assignee:
CHONGQING RUNZE PHARMACEUTICAL (CN)
International Classes:
A61P25/08; A61K31/4015
Foreign References:
CN102603607A2012-07-25
CN105330582A2016-02-17
CN102249977A2011-11-23
CN102600130A2012-07-25
Other References:
CHEMICAL ABSTRACTS, Columbus, Ohio, US; abstract no. 62613-82-5
See also references of EP 3530272A4
Attorney, Agent or Firm:
CHONGQING HONGXU PATENT AGENCY CO., LTD. (CN)
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