Title:
NOVEL CRYSTALS
Document Type and Number:
WIPO Patent Application WO/2004/020433
Kind Code:
A1
Abstract:
Crystals of 4,6-dimethyl-4’-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]nicotinanilide having an excellent calcium release-dependent calcium channel inhibitory effect and an excellent IL-2 production inhibitory activity are obtained. It is found out that this compound occurs in two crystal polymorphisms both of which are appropriate as starting materials for producing medicinal compositions.
Inventors:
KUBOTA HIROKAZU (JP)
IWAOKA KIYOSHI (JP)
YAMAGUCHI SOU (JP)
YOKOTA MASAKI (JP)
IWAOKA KIYOSHI (JP)
YAMAGUCHI SOU (JP)
YOKOTA MASAKI (JP)
Application Number:
PCT/JP2003/010769
Publication Date:
March 11, 2004
Filing Date:
August 26, 2003
Export Citation:
Assignee:
YAMANOUCHI PHARMA CO LTD (JP)
KUBOTA HIROKAZU (JP)
IWAOKA KIYOSHI (JP)
YAMAGUCHI SOU (JP)
YOKOTA MASAKI (JP)
KUBOTA HIROKAZU (JP)
IWAOKA KIYOSHI (JP)
YAMAGUCHI SOU (JP)
YOKOTA MASAKI (JP)
International Classes:
A61P1/04; A61P1/06; A61P1/18; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P19/02; A61P29/00; A61P35/00; A61P37/02; A61P37/06; A61P37/08; A61P39/00; A61P43/00; C07D401/12; (IPC1-7): C07D401/12; A61K31/4439; A61P1/04; A61P1/06; A61P1/18; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P19/02; A61P29/00; A61P35/00; A61P37/02; A61P37/06; A61P37/08; A61P39/00; A61P43/00
Foreign References:
| EP1024138A1 | 2000-08-02 | |||
| JP2000256358A | 2000-09-19 |
Attorney, Agent or Firm:
Nagai, Shozo c/o Yamanouchi Pharmaceutical Co. Ltd. (Patent Department, 17-1, Hasune 3-chom, Itabashi-ku Tokyo, JP)
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