Title:
NOVEL CYTIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/025319
Kind Code:
A1
Abstract:
A novel cytidine derivative and a pharmaceutical composition and use thereof. The cytidine derivative is represented by formula (I0). The compound can be used for preparing a drug for resisting virus infection.
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Inventors:
ZHANG ZHEFENG (CN)
MENG YUELEI (CN)
MENG YUELEI (CN)
Application Number:
PCT/CN2022/115474
Publication Date:
March 02, 2023
Filing Date:
August 29, 2022
Export Citation:
Assignee:
NANJING ZHIHE MEDICINE TECH CO LTD (CN)
International Classes:
A61K31/7064; A61K31/7068; A61P31/12
Domestic Patent References:
| WO2021159044A1 | 2021-08-12 |
Foreign References:
| CN107427529A | 2017-12-01 | |||
| CN104884462A | 2015-09-02 | |||
| CN111372592A | 2020-07-03 | |||
| CN111971284A | 2020-11-20 | |||
| CN111548384A | 2020-08-18 |
Other References:
P. SURESH JAYASEKARA, MATTHEW O. BARRETT, CHRISTOPHER B. BALL, KYLE A. BROWN, EVA HAMMES, RAMACHANDRAN BALASUBRAMANIAN, T. KENDALL: "4-Alkyloxyimino Derivatives of Uridine-5′-triphosphate: Distal Modification of Potent Agonists as a Strategy for Molecular Probes of P2Y 2 , P2Y 4 , and P2Y 6 Receptors", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 57, no. 9, 8 May 2014 (2014-05-08), US , pages 3874 - 3883, XP055229056, ISSN: 0022-2623, DOI: 10.1021/jm500367e
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