NOVEL DESIGN OF GUIDE RNA AND USES THEREOF - HUIGENE THERAPEUTICS CO LTD

Title:

NOVEL DESIGN OF GUIDE RNA AND USES THEREOF

Document Type and Number:

WIPO Patent Application WO/2023/030340

Kind Code:

A1

Abstract:

Provided is a novel design of guide RNA and uses thereof. In one aspect, the guide RNA comprises a spacer sequence flanked by a direct repeat sequence at both the 5' end and the 3' end of the spacer sequence.

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Inventors:

WANG XING (CN)
SHI LINYU (CN)
YAO XUAN (CN)

Application Number:

PCT/CN2022/115961

Publication Date:

March 09, 2023

Filing Date:

August 30, 2022

Export Citation:

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Assignee:

HUIGENE THERAPEUTICS CO LTD (CN)

International Classes:

A61K48/00; C12N15/90; A61P31/00; A61P35/00; C07K19/00; C12N5/10; C12N9/22; C12N15/10; C12N15/11; C12N15/62; C12N15/861; C12N15/867

Domestic Patent References:

WO2019206233A1	2019-10-31
WO2020028555A2	2020-02-06
WO2018035388A1	2018-02-22

Foreign References:

CN112410377A	2021-02-26
CN112041444A	2020-12-04
US20210222164A1	2021-07-22

Attorney, Agent or Firm:

KING & WOOD MALLESONS (CN)

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