Title:
NOVEL FLUORESCENT PROTEIN
Document Type and Number:
WIPO Patent Application WO/2015/080178
Kind Code:
A1
Abstract:
The present invention provides a fluorescent protein including the same or essentially the same amino acid sequence as the amino acid sequence represented by SEQ ID NO: 2.
Inventors:
NAKAYAMA HIDEKI (JP)
SHIMAMOTO NOBUO (JP)
TAKAHASHI MAYAKO (JP)
SHIMAMOTO NOBUO (JP)
TAKAHASHI MAYAKO (JP)
Application Number:
PCT/JP2014/081308
Publication Date:
June 04, 2015
Filing Date:
November 27, 2014
Export Citation:
Assignee:
KYOTO SANGYO UNIVERSITY (JP)
HORIBA LTD (JP)
HORIBA LTD (JP)
International Classes:
C07K14/435; C12N15/09; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; G01N33/68
Domestic Patent References:
| WO2002077011A2 | 2002-10-03 | |||
| WO2004005508A1 | 2004-01-15 |
Foreign References:
| US20090068732A1 | 2009-03-12 |
Other References:
ZIMMER, M.: "Green Fluorescent Protein (GFP): Applications, Structure, and Related Photophysical Behavior", CHEM. REV., vol. 102, 2002, pages 759 - 781, XP002377402, DOI: doi:10.1021/cr010142r
MIZUNO, H ET AL.: "Photo-Induced Peptide Cleavage in the Green-to-Red Conversion of a Fluorescent Protein", MOL. CELL, vol. 12, 2003, pages 1051 - 1058, XP003011506, DOI: doi:10.1016/S1097-2765(03)00393-9
BOURGEOIS, D. ET AL.: "Reversible Photoswitching in Fluorescent Proteins: a Mechanistic View", IUBMB LIFE, vol. 64, 2012, pages 482 - 491
PEDELACQ, J.-D. ET AL.: "Engineering and Characterization of a Superfolder Green Fluorescent Protein", NAT. BIOTECHNOL., vol. 24, 2005, pages 79 - 88, XP002368364, DOI: doi:10.1038/nbt1172
ITO, Y. ET AL.: "A Novel Mutant of Green Fluorescent Protein with Enhanced Sensitivity for Microanalysis at 488 Nm Excitation", BIOCHEM. BIOPHYS. RES. COMMUN, vol. 264, 1999, pages 556 - 560, XP002954198, DOI: doi:10.1006/bbrc.1999.1541
NAGAI, T ET AL.: "A Variant of Yellow Fluorescent Protein with Fast and Efficient Maturation for Cell-Biological Applications", NAT. BIOTECHNOL., vol. 20, 2002, pages 87 - 90, XP002218913, DOI: doi:10.1038/nbt0102-87
BOWIE ET AL., SCIENCE, vol. 247, 1990, pages 1306 - 1310
KARLIN ET AL., PROC. NATL. ACAD. SCI. USA, vol. 90, 1993, pages 5873 - 5877
ALTSCHUL ET AL., NUCLEIC ACIDS RES., vol. 25, 1997, pages 3389 - 3402
NEEDLEMAN ET AL., J. MOL. BIOL., vol. 48, 1970, pages 444 - 453
MYERS; MILLER, CABIOS, vol. 4, 1988, pages 11 - 17
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444 - 2448
PROC. NATL. ACAD. SCI. USA, vol. 69, 1972, pages 2110
GENE, vol. 17, 1982, pages 107
MOLECULAR GENERAL GENETICS, vol. 168, 1979, pages 111
METHODS IN ENZYMOLOGY, vol. 194, 1991, pages 182 - 187
PROC. NATL. ACAD. SCI. USA, vol. 75, 1978, pages 1929
BIO/TECHNOLOGY, vol. 6, 1988, pages 47 - 55
"New Cell Engineering Experimental Protocol", 1995, article "Cell Engineering", pages: 263 - 267
VIROLOGY, vol. 52, 1973, pages 456
"development of transgenic animal", 2001, CMC PUBLISHING
See also references of EP 3081642A4
MIZUNO, H ET AL.: "Photo-Induced Peptide Cleavage in the Green-to-Red Conversion of a Fluorescent Protein", MOL. CELL, vol. 12, 2003, pages 1051 - 1058, XP003011506, DOI: doi:10.1016/S1097-2765(03)00393-9
BOURGEOIS, D. ET AL.: "Reversible Photoswitching in Fluorescent Proteins: a Mechanistic View", IUBMB LIFE, vol. 64, 2012, pages 482 - 491
PEDELACQ, J.-D. ET AL.: "Engineering and Characterization of a Superfolder Green Fluorescent Protein", NAT. BIOTECHNOL., vol. 24, 2005, pages 79 - 88, XP002368364, DOI: doi:10.1038/nbt1172
ITO, Y. ET AL.: "A Novel Mutant of Green Fluorescent Protein with Enhanced Sensitivity for Microanalysis at 488 Nm Excitation", BIOCHEM. BIOPHYS. RES. COMMUN, vol. 264, 1999, pages 556 - 560, XP002954198, DOI: doi:10.1006/bbrc.1999.1541
NAGAI, T ET AL.: "A Variant of Yellow Fluorescent Protein with Fast and Efficient Maturation for Cell-Biological Applications", NAT. BIOTECHNOL., vol. 20, 2002, pages 87 - 90, XP002218913, DOI: doi:10.1038/nbt0102-87
BOWIE ET AL., SCIENCE, vol. 247, 1990, pages 1306 - 1310
KARLIN ET AL., PROC. NATL. ACAD. SCI. USA, vol. 90, 1993, pages 5873 - 5877
ALTSCHUL ET AL., NUCLEIC ACIDS RES., vol. 25, 1997, pages 3389 - 3402
NEEDLEMAN ET AL., J. MOL. BIOL., vol. 48, 1970, pages 444 - 453
MYERS; MILLER, CABIOS, vol. 4, 1988, pages 11 - 17
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444 - 2448
PROC. NATL. ACAD. SCI. USA, vol. 69, 1972, pages 2110
GENE, vol. 17, 1982, pages 107
MOLECULAR GENERAL GENETICS, vol. 168, 1979, pages 111
METHODS IN ENZYMOLOGY, vol. 194, 1991, pages 182 - 187
PROC. NATL. ACAD. SCI. USA, vol. 75, 1978, pages 1929
BIO/TECHNOLOGY, vol. 6, 1988, pages 47 - 55
"New Cell Engineering Experimental Protocol", 1995, article "Cell Engineering", pages: 263 - 267
VIROLOGY, vol. 52, 1973, pages 456
"development of transgenic animal", 2001, CMC PUBLISHING
See also references of EP 3081642A4
Attorney, Agent or Firm:
TAKASHIMA, HAJIME (JP)
Takashima 1 (JP)
Takashima 1 (JP)
Download PDF:
Previous Patent: ANTITHROMBOTIC MATERIAL
Next Patent: LASER CUTTING METHOD AND DEVICE, AND AUTOMATIC PROGRAMMING DEVICE
Next Patent: LASER CUTTING METHOD AND DEVICE, AND AUTOMATIC PROGRAMMING DEVICE