Title:
NOVEL FUCOSE ISOMERASE AND FUCOSE PRODUCTION METHOD USING SAME
Document Type and Number:
WIPO Patent Application WO/2021/040385
Kind Code:
A1
Abstract:
The present invention relates to a novel fucose isomerase and a fucose production method using same. More specifically, in a reversible reaction between L-fucose and L-fuculose, an L-fucose isomerase, derived from a Raoultella sp. KDH 14 strain isolated from abalone intestines, favors the reaction progressing from L-fuculose to L-fucose, and thus the present invention provides the effect of applying same to the production of L-fucose.
Inventors:
KIM KYOUNG HEON (KR)
NAM KI HYUN (KR)
KIM DO HYOUNG (KR)
KIM IN JEONG (KR)
NAM KI HYUN (KR)
KIM DO HYOUNG (KR)
KIM IN JEONG (KR)
Application Number:
PCT/KR2020/011336
Publication Date:
March 04, 2021
Filing Date:
August 25, 2020
Export Citation:
Assignee:
UNIV KOREA RES & BUS FOUND (KR)
International Classes:
C12N9/90; C12N15/52; C12P19/02; C12P19/24
Foreign References:
| KR20180026820A | 2018-03-14 |
Other References:
DATABASE Protein 25 October 2019 (2019-10-25), ANONYMOUS: "MULTISPECIES: L-fucose isomerase [Raoultella]", XP055786714, retrieved from Genbank Database accession no. WP_104896882
YO-HAN JU; DEOK-KUN OH: "Characterization of a recombinant l-fucose isomerase from Caldicellulosiruptor saccharolyticus that isomerizes l-fucose, d-arabinose, d-altrose, and l-galactose", BIOTECHNOLOGY LETTERS, vol. 32, no. 2, 25 October 2009 (2009-10-25), pages 299 - 304, XP019766798, ISSN: 1573-6776, DOI: 10.1007/s10529-009-0154-7
MAURICE GREEN , SEYMOUR S COHEN: "Enzymatic conversion of L-fucose to L-fuculose", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 2019, no. 2, 1 April 1956 (1956-04-01), pages 557 - 568, XP055786682, DOI: 10.1016/S0021-9258(18)65716-3
DATABASE Nucleotide 31 January 2014 (2014-01-31), ANONYMOUS: "Raoultella ornithinolytica B6, complete genome", XP009526439, retrieved from Genbank Database accession no. CP004142
YO-HAN JU; DEOK-KUN OH: "Characterization of a recombinant l-fucose isomerase from Caldicellulosiruptor saccharolyticus that isomerizes l-fucose, d-arabinose, d-altrose, and l-galactose", BIOTECHNOLOGY LETTERS, vol. 32, no. 2, 25 October 2009 (2009-10-25), pages 299 - 304, XP019766798, ISSN: 1573-6776, DOI: 10.1007/s10529-009-0154-7
MAURICE GREEN , SEYMOUR S COHEN: "Enzymatic conversion of L-fucose to L-fuculose", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 2019, no. 2, 1 April 1956 (1956-04-01), pages 557 - 568, XP055786682, DOI: 10.1016/S0021-9258(18)65716-3
DATABASE Nucleotide 31 January 2014 (2014-01-31), ANONYMOUS: "Raoultella ornithinolytica B6, complete genome", XP009526439, retrieved from Genbank Database accession no. CP004142
Attorney, Agent or Firm:
DANA PATENT LAW FIRM (KR)
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