Title:
NOVEL GLUCOSE DEHYDROGENASE
Document Type and Number:
WIPO Patent Application WO/2021/125332
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing an FAD-GDH that has high heat stability and, in particular, improved practical usability for a glucose sensor. Provided is a novel FAD-GDH having the following characteristics: (1) function: catalyzing a reaction of oxidizing a hydroxyl group of glucose in the presence of an electron acceptor to form glucono-δ-lactone; (2) heat stability: after a thermal treatment at 50°C for 20 minutes, showing a relative residual activity of 60% or higher; and (3) molecular weight: approximately 68 kDa (measured by SDS-PAGE after removing sugar chains).
Inventors:
MATSUDA KANKI (JP)
IDO HIROKI (JP)
SUGIURA TOSHIYUKI (JP)
KATSUMATA NAOTO (JP)
IDO HIROKI (JP)
SUGIURA TOSHIYUKI (JP)
KATSUMATA NAOTO (JP)
Application Number:
PCT/JP2020/047475
Publication Date:
June 24, 2021
Filing Date:
December 18, 2020
Export Citation:
Assignee:
AMANO ENZYME INC (JP)
International Classes:
C12M1/40; C12N9/04; C12N15/53; C12Q1/32
Domestic Patent References:
| WO2015060150A1 | 2015-04-30 |
Foreign References:
| JP2016007193A | 2016-01-18 | |||
| JP2016007192A | 2016-01-18 | |||
| JP2016208916A | 2016-12-15 |
Attorney, Agent or Firm:
TANAKA, Junya et al. (JP)
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