Title:
NOVEL GLUTAMINE ANALOGS
Document Type and Number:
WIPO Patent Application WO/2022/022612
Kind Code:
A1
Abstract:
The invention relates to novel glutamine analogs shown as the formula I, a composition containing the glutamine analogs and the use thereof.
Inventors:
LI RUNZE (CN)
MA CUNBO (CN)
LIAN ZHENCHANG (CN)
XIONG JING (CN)
ZHANG LEI (CN)
MA CUNBO (CN)
LIAN ZHENCHANG (CN)
XIONG JING (CN)
ZHANG LEI (CN)
Application Number:
PCT/CN2021/109134
Publication Date:
February 03, 2022
Filing Date:
July 29, 2021
Export Citation:
Assignee:
JACOBIO PHARMACEUTICALS CO LTD (CN)
International Classes:
C07D295/182; A61K31/40; A61K31/445; A61K31/4965; A61K31/535; A61P35/00; C07D205/04; C07D207/27; C07D209/34; C07D209/46; C07D209/48; C07D209/54; C07D211/16; C07D211/38; C07D211/46; C07D211/56; C07D211/58; C07D211/62; C07D211/70; C07D211/72; C07D211/74; C07D211/76; C07D211/88; C07D213/64; C07D215/08; C07D215/233; C07D217/24; C07D221/20; C07D223/10; C07D239/10; C07D241/08; C07D265/06; C07D265/10; C07D265/32; C07D267/06; C07D279/12; C07D401/04; C07D471/04; C07D487/04; C07D491/107; C07K5/06
Domestic Patent References:
| WO2019071110A1 | 2019-04-11 | |||
| WO2020150639A1 | 2020-07-23 |
Foreign References:
| CN108290827A | 2018-07-17 | |||
| CN108135872A | 2018-06-08 | |||
| CN110088120A | 2019-08-02 | |||
| CN108135875A | 2018-06-08 |
Other References:
NEDELCOVYCH MICHAEL T., TENORA LUKÁŠ, KIM BOE-HYUN, KELSCHENBACH JENNIFER, CHAO WEI, HADAS ERAN, JANČAŘÍK ANDREJ, PRCHALOVÁ EVA, Z: "N‑(Pivaloyloxy)alkoxy-carbonyl Prodrugs of the Glutamine Antagonist 6‑Diazo-5-oxo‑L‑norleucine (DON) as a Potential Treatment for HIV Associated Neurocognitive Disorders", JOURNAL OF MEDICINAL CHEMISTRY, vol. 60, no. 16, 24 August 2017 (2017-08-24), US , pages 7186 - 7198, XP055896332, ISSN: 0022-2623, DOI: 10.1021/acs.jmedchem.7b00966
TENORA LUKÁŠ; ALT JESSE; DASH RANJEET P; GADIANO ALEXANDRA J; NOVOTNÁ KATEŘINA; VEERAVALLI VIJAYABHASKAR; LAM JENNY; KIRKPATRICK Q: "-norleucine (DON) Using Substituted Acetylated Lysine Prodrugs", JOURNAL OF MEDICINAL CHEMISTRY, vol. 62, no. 7, 11 April 2019 (2019-04-11), US , pages 3524 - 3538, XP055805617, ISSN: 0022-2623, DOI: 10.1021/acs.jmedchem.8b02009
TENORA LUKÁŠ; ALT JESSE; DASH RANJEET P; GADIANO ALEXANDRA J; NOVOTNÁ KATEŘINA; VEERAVALLI VIJAYABHASKAR; LAM JENNY; KIRKPATRICK Q: "-norleucine (DON) Using Substituted Acetylated Lysine Prodrugs", JOURNAL OF MEDICINAL CHEMISTRY, vol. 62, no. 7, 11 April 2019 (2019-04-11), US , pages 3524 - 3538, XP055805617, ISSN: 0022-2623, DOI: 10.1021/acs.jmedchem.8b02009
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