Title:
NOVEL GLUTAMINE ANALOGS
Document Type and Number:
WIPO Patent Application WO/2022/078416
Kind Code:
A1
Abstract:
Glutamine analogs, a composition containing the glutamine analogs and the use thereof.
Inventors:
LI RUNZE (CN)
MA CUNBO (CN)
LIAN ZHENCHANG (CN)
XIONG JING (CN)
WANG YANPING (CN)
LONG WEI (CN)
MA CUNBO (CN)
LIAN ZHENCHANG (CN)
XIONG JING (CN)
WANG YANPING (CN)
LONG WEI (CN)
Application Number:
PCT/CN2021/123674
Publication Date:
April 21, 2022
Filing Date:
October 14, 2021
Export Citation:
Assignee:
JACOBIO PHARMACEUTICALS CO LTD (CN)
International Classes:
C07C227/14; A61K31/404; A61K31/66; A61P35/00; C07D209/10; C07D317/40; C07F9/06
Domestic Patent References:
| WO2019071110A1 | 2019-04-11 |
Foreign References:
| CN108290827A | 2018-07-17 | |||
| CN108348492A | 2018-07-31 |
Other References:
DATABASE REGISTRY 29 August 2018 (2018-08-29), ANONYMOUS : "L-Norleucine, 6-diazenylidene-N-[[(R)-(2,2-dimethyl-1- oxopropoxy)phenylmethoxy]carbonyl]-5-oxo-, 1-methylethyl ester (CA INDEX NAME) ", XP055922274, retrieved from STN Database accession no. 2241788-97-4
DATABASE REGISTRY 29 August 2018 (2018-08-29), ANONYMOUS : "L-Norleucine, 6-diazenylidene-N-[[(S)-(2,2-dimethyl-1- oxopropoxy)phenylmethoxy]carbonyl]-5-oxo-, 1-methylethyl ester (CA INDEX NAME) ", XP055922278, retrieved from STN Database accession no. 2241788-96-3
DATABASE REGISTRY 29 July 2018 (2018-07-29), ANONYMOUS : "Heptanoic acid, 2-[bis[(1,1-dimethylethoxy)carbonyl]amino]-7-diazo-6-oxo-, 1,1-dimethylethyl ester, (2S)- (CA INDEX NAME)", XP055922280, retrieved from STN Database accession no. 2232131-70-1
DATABASE REGISTRY 29 July 2018 (2018-07-29), ANONYMOUS : "L-Norleucine, 6-diazenylidene-N,N-bis[(1,1-dimethylethoxy)carbonyl]-5-oxo- , 1,1-dimethylethyl ester (CA INDEX NAME) ", XP055922282, retrieved from STN Database accession no. 2232131-59-6
DATABASE REGISTRY 16 July 2018 (2018-07-16), ANONYMOUS: "RN 2230815-45-7 L-Norleucine, 6-diazo-N-[(1,1-dimethylethoxy)carbonyl]-5-oxo, methyl", XP009536276, retrieved from STN Database accession no. 2230815-45-7
DATABASE REGISTRY 3 April 2018 (2018-04-03), ANONYMOUS : "INDEX NAME NOT YET ASSIGNED ", XP055922288, retrieved from STN Database accession no. 2204460-16-0
DATABASE REGISTRY 2 March 2017 (2017-03-02), ANONYMOUS : "L-Norleucine, 6-diazo-N2-[[(1S)-1-(2-methyl-1-oxopropoxy)ethoxy]carbonyl]- 5-oxo-, ethyl ester (CA INDEX NAME)", XP055922289, retrieved from STN Database accession no. 2079939-28-7
DATABASE REGISTRY 2 March 2017 (2017-03-02), ANONYMOUS : "L-Norleucine, N-[[[4-(acetyloxy)phenyl]methoxy]carbonyl]-6-diazo-5-oxo-, ethyl ester (CA INDEX NAME)", XP055922291, retrieved from STN Database accession no. 2079939-26-5
DATABASE REGISTRY 2 March 2017 (2017-03-02), ANONYMOUS : "L-Norleucine, 6-diazo-5-oxo-, 1-methylethyl ester (CA INDEX NAME)", XP055922293, retrieved from STN Database accession no. 2079939-24-3
DATABASE REGISTRY 2 March 2017 (2017-03-02), ANONYMOUS : "L-Norleucine, 6-diazo-N-[[1-(2,2-dimethyl-1-oxopropoxy)-2- methylpropoxy]carbonyl]-5-oxo-, 1-methylethyl ester (CA INDEX NAME) ", XP055922297, retrieved from STN Database accession no. 2079939-22-1
DATABASE REGISTRY 2 March 2017 (2017-03-02), ANONYMOUS : "L-Norleucine, 6-diazo-N-[[1-(2-methyl-1-oxopropoxy)ethoxy]carbonyl]-5-oxo- , ethyl ester (CA INDEX NAME) ", XP055922298, retrieved from STN Database accession no. 2079939-21-0
DATABASE REGISTRY 2 March 2017 (2017-03-02), ANONYMOUS : "L-Norleucine, 6-diazo-N-[[1-(2,2-dimethyl-1-oxopropoxy)ethoxy]carbonyl]-5- oxo-, ethyl ester (CA INDEX NAME) ", XP055922300, retrieved from STN Database accession no. 2079939-20-9
DATABASE REGISTRY 2 March 2017 (2017-03-02), ANONYMOUS : "Norleucine, 6-diazo-N-[[1-(2-methyl-1-oxopropoxy)ethoxy]carbonyl]-5-oxo-, ethyl ester (CA INDEX NAME) ", XP055922304, retrieved from STN Database accession no. 2079939-19-6
DATABASE REGISTRY 2 March 2017 (2017-03-02), ANONYMOUS : "L-Norleucine, 6-diazo-5-oxo-N2-[(2-propen-1-yloxy)carbonyl]- (CA INDEX NAME)", XP055922305, retrieved from STN Database accession no. 2079939-15-2
DATABASE REGISTRY 16 November 1984 (1984-11-16), ANONYMOUS : "L-Serine, O-(2-diazoacetyl)-(CA INDEX NAME) OTHER CA INDEX NAMES: CN -L-Serine, diazoacetate (ester) (9CI) CN -O-(2-Diazoacetyl)-L-serine CN -Serine, diazoacetate (ester), L-(6CI, 8CI)", XP055922308, retrieved from STN Database accession no. 115-02-6
DATABASE REGISTRY 29 August 2018 (2018-08-29), ANONYMOUS : "L-Norleucine, 6-diazenylidene-N-[[(S)-(2,2-dimethyl-1- oxopropoxy)phenylmethoxy]carbonyl]-5-oxo-, 1-methylethyl ester (CA INDEX NAME) ", XP055922278, retrieved from STN Database accession no. 2241788-96-3
DATABASE REGISTRY 29 July 2018 (2018-07-29), ANONYMOUS : "Heptanoic acid, 2-[bis[(1,1-dimethylethoxy)carbonyl]amino]-7-diazo-6-oxo-, 1,1-dimethylethyl ester, (2S)- (CA INDEX NAME)", XP055922280, retrieved from STN Database accession no. 2232131-70-1
DATABASE REGISTRY 29 July 2018 (2018-07-29), ANONYMOUS : "L-Norleucine, 6-diazenylidene-N,N-bis[(1,1-dimethylethoxy)carbonyl]-5-oxo- , 1,1-dimethylethyl ester (CA INDEX NAME) ", XP055922282, retrieved from STN Database accession no. 2232131-59-6
DATABASE REGISTRY 16 July 2018 (2018-07-16), ANONYMOUS: "RN 2230815-45-7 L-Norleucine, 6-diazo-N-[(1,1-dimethylethoxy)carbonyl]-5-oxo, methyl", XP009536276, retrieved from STN Database accession no. 2230815-45-7
DATABASE REGISTRY 3 April 2018 (2018-04-03), ANONYMOUS : "INDEX NAME NOT YET ASSIGNED ", XP055922288, retrieved from STN Database accession no. 2204460-16-0
DATABASE REGISTRY 2 March 2017 (2017-03-02), ANONYMOUS : "L-Norleucine, 6-diazo-N2-[[(1S)-1-(2-methyl-1-oxopropoxy)ethoxy]carbonyl]- 5-oxo-, ethyl ester (CA INDEX NAME)", XP055922289, retrieved from STN Database accession no. 2079939-28-7
DATABASE REGISTRY 2 March 2017 (2017-03-02), ANONYMOUS : "L-Norleucine, N-[[[4-(acetyloxy)phenyl]methoxy]carbonyl]-6-diazo-5-oxo-, ethyl ester (CA INDEX NAME)", XP055922291, retrieved from STN Database accession no. 2079939-26-5
DATABASE REGISTRY 2 March 2017 (2017-03-02), ANONYMOUS : "L-Norleucine, 6-diazo-5-oxo-, 1-methylethyl ester (CA INDEX NAME)", XP055922293, retrieved from STN Database accession no. 2079939-24-3
DATABASE REGISTRY 2 March 2017 (2017-03-02), ANONYMOUS : "L-Norleucine, 6-diazo-N-[[1-(2,2-dimethyl-1-oxopropoxy)-2- methylpropoxy]carbonyl]-5-oxo-, 1-methylethyl ester (CA INDEX NAME) ", XP055922297, retrieved from STN Database accession no. 2079939-22-1
DATABASE REGISTRY 2 March 2017 (2017-03-02), ANONYMOUS : "L-Norleucine, 6-diazo-N-[[1-(2-methyl-1-oxopropoxy)ethoxy]carbonyl]-5-oxo- , ethyl ester (CA INDEX NAME) ", XP055922298, retrieved from STN Database accession no. 2079939-21-0
DATABASE REGISTRY 2 March 2017 (2017-03-02), ANONYMOUS : "L-Norleucine, 6-diazo-N-[[1-(2,2-dimethyl-1-oxopropoxy)ethoxy]carbonyl]-5- oxo-, ethyl ester (CA INDEX NAME) ", XP055922300, retrieved from STN Database accession no. 2079939-20-9
DATABASE REGISTRY 2 March 2017 (2017-03-02), ANONYMOUS : "Norleucine, 6-diazo-N-[[1-(2-methyl-1-oxopropoxy)ethoxy]carbonyl]-5-oxo-, ethyl ester (CA INDEX NAME) ", XP055922304, retrieved from STN Database accession no. 2079939-19-6
DATABASE REGISTRY 2 March 2017 (2017-03-02), ANONYMOUS : "L-Norleucine, 6-diazo-5-oxo-N2-[(2-propen-1-yloxy)carbonyl]- (CA INDEX NAME)", XP055922305, retrieved from STN Database accession no. 2079939-15-2
DATABASE REGISTRY 16 November 1984 (1984-11-16), ANONYMOUS : "L-Serine, O-(2-diazoacetyl)-(CA INDEX NAME) OTHER CA INDEX NAMES: CN -L-Serine, diazoacetate (ester) (9CI) CN -O-(2-Diazoacetyl)-L-serine CN -Serine, diazoacetate (ester), L-(6CI, 8CI)", XP055922308, retrieved from STN Database accession no. 115-02-6
Attorney, Agent or Firm:
NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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