Title:
NOVEL HEMOPOIETIN RECEPTOR PROTEINS
Document Type and Number:
WIPO Patent Application WO/1999/067290
Kind Code:
A1
Abstract:
Novel hemopoietin receptor proteins (proteins having the amino acid sequences represented by SEQ ID NOS: 1, 3, 5, 7, 19 and 21); proteins having amino acid sequences derived from the amino acid sequences of the above proteins by modification via deletion, addition or substitution of one or more amino acids; genes encoding these proteins; a process for producing these proteins; and utilization of these proteins and genes.
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Inventors:
NOMURA HITOSHI (JP)
MAEDA MASATSUGU (JP)
MAEDA MASATSUGU (JP)
Application Number:
PCT/JP1999/003351
Publication Date:
December 29, 1999
Filing Date:
June 23, 1999
Export Citation:
Assignee:
CHUGAI RES INST MOLECULAR MED (JP)
NOMURA HITOSHI (JP)
MAEDA MASATSUGU (JP)
NOMURA HITOSHI (JP)
MAEDA MASATSUGU (JP)
International Classes:
C07K14/715; C12N15/12; (IPC1-7): C07K14/715; C07K16/16; C07K16/28; C07K19/00; C12N5/10; C12N15/12; C12P21/02; C12Q1/68; G01N33/50; G01N33/53
Other References:
ROBB L, ET AL.: "RECEPTOR ALPHA-CHAIN AND A RELATED LOCUS STRUCTURAL ANALYSIS OF THE GENE ENCODING THE MURINE INTERLEUKIN-11", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, vol. 271, no. 23, 7 June 1996 (1996-06-07), US, pages 13754 - 13761, XP002922183, ISSN: 0021-9258, DOI: 10.1074/jbc.271.23.13754
GAINSFORD T, ET AL.: "LEPTIN CAN INDUCE PROLIFERATION DIFFERENTIATION AND FUNCTIONAL ACTIVATION OF HEMOPOIETIC CELLS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, US, vol. 93, 1 December 1996 (1996-12-01), US, pages 14564 - 14568, XP002921615, ISSN: 0027-8424, DOI: 10.1073/pnas.93.25.14564
HILTON D. J., ET AL.: "CLONING AND CHARACTERIZATION OF A BINDING SUBUNIT OF THE INTERLEUKIN 13 RECEPTOR THAT IS ALSO A COMPONENT OF THE INTERLEUKIN4 RECEPTOR.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, US, vol. 93., 1 January 1996 (1996-01-01), US, pages 497 - 501., XP002922184, ISSN: 0027-8424, DOI: 10.1073/pnas.93.1.497
See also references of EP 1088831A4
GAINSFORD T, ET AL.: "LEPTIN CAN INDUCE PROLIFERATION DIFFERENTIATION AND FUNCTIONAL ACTIVATION OF HEMOPOIETIC CELLS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, US, vol. 93, 1 December 1996 (1996-12-01), US, pages 14564 - 14568, XP002921615, ISSN: 0027-8424, DOI: 10.1073/pnas.93.25.14564
HILTON D. J., ET AL.: "CLONING AND CHARACTERIZATION OF A BINDING SUBUNIT OF THE INTERLEUKIN 13 RECEPTOR THAT IS ALSO A COMPONENT OF THE INTERLEUKIN4 RECEPTOR.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, US, vol. 93., 1 January 1996 (1996-01-01), US, pages 497 - 501., XP002922184, ISSN: 0027-8424, DOI: 10.1073/pnas.93.1.497
See also references of EP 1088831A4
Attorney, Agent or Firm:
Shimizu, Hatsushi (Oroshi-machi Tsuchiura-shi Ibaraki, JP)
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