Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
NOVEL HETEROCYCLE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2019/212256
Kind Code:
A1
Abstract:
The present invention relates to a novel heterocycle derivative, a salt thereof, or an isomer thereof. More specifically, the present invention relates to a novel heterocycle derivative effective for the therapy of hair loss such as androgenic alopecia and alopecia areata and having an excellent preventive effect of hair loss, a salt or isomer thereof, and a composition comprising same as an effective ingredient for prevention of hair loss.

Inventors:
HONG WOO SANG (KR)
CHA JOO YOUNG (KR)
CHOI SUN EA (KR)
IM ISAK (KR)
YUN CHI-HO (KR)
JANG JAE HO (KR)
JUNG CHAE LIM (KR)
CHIN SEI HO (KR)
KIM JIKNYEO (KR)
KIM JOONGSOO (KR)
LEE SANG HAK (KR)
Application Number:
KR2019/005261
Publication Date:
November 07, 2019
Filing Date:
May 02, 2019
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
JW PHARMACEUTICAL CORP (KR)
International Classes:
C07D471/04; A61K8/49; A61K31/437; A61P17/14; A61Q7/00
Domestic Patent References:
WO2003068773A12003-08-21
WO2006091737A12006-08-31
WO2004018473A22004-03-04
WO2013067302A12013-05-10
WO2018208132A12018-11-15
Foreign References:
JPH03287513A1991-12-18
KR20100121222A2010-11-17
KR20150085962A2015-07-27
Other References:
MARTEL J.L.BADRI T.: "Anatomy, Head, Hair, Follicle. Book", 10 January 2018, STATPEARLS PUBLISHING LLC
BOTCHKAREV V.A.KISHIMOTO J.: "Molecular control of epithelial-mesenchymal interactions during hair follicle cycling", J INVESTIG. DERMATOL. SYMP. PROC., vol. 8, 2003, pages 46 - 55, XP055058772, DOI: 10.1046/j.1523-1747.2003.12171.x
BOTCHKAREV V.A.BATCHKAREVA N.V.NAKAMURA M: "Noggin is required for induction of the hair follicle growth phase in postnatal skin", FASEB J, vol. 15, 2001, pages 2205 - 2214, XP001161202, DOI: 10.1096/fj.01-0207com
MINGXING LEILI YANGCHENG-MING CHUONG: "Getting to the Core of the Dermal Papilla", J. INVEST. DERMATOL., vol. 137, 2017, pages 2250 - 2253
KWACK M.H.SUNG Y.K.CHUNG E.J.IM S.U.AHN J.S.KIM M.K.KIM J.C.: "Dihydrotestosterone-inducible dickkopf 1 from balding dermal papilla cells causes apoptosis in follicular keratinocytes", J. INVEST. DERMATOL., vol. 128, 2008, pages 262 - 269
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
Download PDF: