Title:
NOVEL HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION FOR INHIBITING AUTOTAXIN COMPRISING THE SAME
Document Type and Number:
WIPO Patent Application WO/2024/019597
Kind Code:
A1
Abstract:
The present invention provides: a novel heterocyclic compound, a hydrate thereof, a solvate thereof, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating a disease related to autotaxin activity, the composition comprising same as an active ingredient. The heterocyclic compound of the present invention exhibits excellent inhibitory activity against autotaxin, and thus can be used in the treatment and prevention of diseases related to autotaxin inhibition, such as fibrotic diseases, inflammatory diseases, autoimmune diseases, respiratory diseases, cardiovascular diseases, metabolic diseases, cancer and cancer metastasis, ocular diseases, chronic pruritus in a cholestatic form and other forms, and acute or chronic organ transplant rejection.
Inventors:
LEE BONG YONG (KR)
SHIN YOUNG AH (KR)
KIM SHIN AE (KR)
HAN NA RA (KR)
NOH HYEON SEOK (KR)
SHIN SOO JEONG (KR)
LEE JAE SANG (KR)
LEE JAE UN (KR)
CHO YOUNG KYOUNG (KR)
SHIN YOUNG AH (KR)
KIM SHIN AE (KR)
HAN NA RA (KR)
NOH HYEON SEOK (KR)
SHIN SOO JEONG (KR)
LEE JAE SANG (KR)
LEE JAE UN (KR)
CHO YOUNG KYOUNG (KR)
Application Number:
PCT/KR2023/010621
Publication Date:
January 25, 2024
Filing Date:
July 21, 2023
Export Citation:
Assignee:
NEXTGEN BIOSCIENCE CO LTD (KR)
International Classes:
C07D413/14; A61K31/397; A61K31/4439; A61K31/497; A61K31/506; A61P7/02; A61P29/00; A61P35/00; A61P37/00; C07D403/14
Domestic Patent References:
| WO2002080928A1 | 2002-10-17 |
Foreign References:
| KR20150095888A | 2015-08-21 | |||
| KR20210062023A | 2021-05-28 | |||
| KR20210034098A | 2021-03-29 | |||
| KR20220038438A | 2022-03-28 |
Attorney, Agent or Firm:
PHIL & ONZI INT'L PATENT & LAW FIRM (KR)
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