Title:
NOVEL HETEROCYCLIC COMPOUND
Document Type and Number:
WIPO Patent Application WO/2023/185811
Kind Code:
A1
Abstract:
The present invention relates to a novel heterocyclic compound; specifically, provided in the present invention are a compound represented by formula (I) or pharmaceutically acceptable salts, solvates, polymorphs or isomers thereof, a pharmaceutical composition comprising same, and the use of same in preparation of a drug for treating MAT2A related diseases.
Inventors:
LOU ZHENBANG (CN)
HU WENQI (CN)
ZHANG QUANHAO (CN)
WANG YELIU (CN)
SHANG XIANXING (CN)
LIU SHUANG (CN)
SHI JUNFEN (CN)
WANG HE (CN)
HU WENQI (CN)
ZHANG QUANHAO (CN)
WANG YELIU (CN)
SHANG XIANXING (CN)
LIU SHUANG (CN)
SHI JUNFEN (CN)
WANG HE (CN)
Application Number:
PCT/CN2023/084314
Publication Date:
October 05, 2023
Filing Date:
March 28, 2023
Export Citation:
Assignee:
SHOUYAO HOLDINGS BEIJING CO LTD (CN)
International Classes:
A61K31/4375; C07D215/54; A61K31/4706; A61P35/00; C07D215/22; C07D215/42; C07D471/04
Domestic Patent References:
| WO2022228515A1 | 2022-11-03 | |||
| WO2021254529A1 | 2021-12-23 | |||
| WO2022053022A1 | 2022-03-17 | |||
| WO2001046190A1 | 2001-06-28 |
Foreign References:
| CN1211569A | 1999-03-24 | |||
| CN101516853A | 2009-08-26 |
Other References:
DATABASE Registry CAS; 10 December 2008 (2008-12-10), ANONYMOUS : "1,8-Naphthyridine-3-carb oxylic acid, 4-amino-1-cyclopent yl-1,2-dihydro-2-oxo -, ethyl ester", XP093096863, retrieved from STN Database accession no. 1082595-85-4
I. V. UKRAINETS ; L. V. SIDORENKO ; O. V. GOROKHOVA: "4-Hydroxyquinol-2-ones. 86. Synthesis of Methyl (Ethyl) Esters of 1-Substituted 4-Amino-2-oxoquinoline-3-carboxylic Acids", CHEMISTRY OF HETEROCYCLIC COMPOUNDS, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NL, vol. 41, no. 9, 1 September 2005 (2005-09-01), NL , pages 1151 - 1157, XP019276439, ISSN: 1573-8353
SHANMUGASUNDARAM P, HARIKRISHNAN N, AANANDINI VIJEY, KUMAR SATHISH, SATEESH J N: "Synthesis and biological evaluation of pyrido(2, 3-d)pyrimidine-carboxylate derivatives", INDIAN JOURNAL OF CHEMISTRY, vol. 50B, 1 March 2011 (2011-03-01), pages 284 - 289, XP093096869
A. M. RAMADAN, G. H. ELGEMEIE, T. KAPPE: "Synthesis of some novel azido- and tetrazoloquinoline-3-carbonitriles and their conversion into 2,4-diaminoquinoline-3-carbonitriles", JOURNAL OF CHEMICAL RESEARCH - SYNOPSES, SCIENCE REVIEWS LTD., GB, vol. 2, 1 January 2005 (2005-01-01), GB , pages 82 - 85, XP008175164, ISSN: 0308-2342, DOI: 10.3184/0308234054497100
I. V. UKRAINETS ; L. V. SIDORENKO ; O. V. GOROKHOVA: "4-Hydroxyquinol-2-ones. 86. Synthesis of Methyl (Ethyl) Esters of 1-Substituted 4-Amino-2-oxoquinoline-3-carboxylic Acids", CHEMISTRY OF HETEROCYCLIC COMPOUNDS, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NL, vol. 41, no. 9, 1 September 2005 (2005-09-01), NL , pages 1151 - 1157, XP019276439, ISSN: 1573-8353
SHANMUGASUNDARAM P, HARIKRISHNAN N, AANANDINI VIJEY, KUMAR SATHISH, SATEESH J N: "Synthesis and biological evaluation of pyrido(2, 3-d)pyrimidine-carboxylate derivatives", INDIAN JOURNAL OF CHEMISTRY, vol. 50B, 1 March 2011 (2011-03-01), pages 284 - 289, XP093096869
A. M. RAMADAN, G. H. ELGEMEIE, T. KAPPE: "Synthesis of some novel azido- and tetrazoloquinoline-3-carbonitriles and their conversion into 2,4-diaminoquinoline-3-carbonitriles", JOURNAL OF CHEMICAL RESEARCH - SYNOPSES, SCIENCE REVIEWS LTD., GB, vol. 2, 1 January 2005 (2005-01-01), GB , pages 82 - 85, XP008175164, ISSN: 0308-2342, DOI: 10.3184/0308234054497100
Attorney, Agent or Firm:
CN-KNOWHOW INTELLECTUAL PROPERTY AGENT LIMITED (CN)
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