NOVEL HUMAN CC CHEMOKINE

WIPO Patent Application WO/1997/012914

A1

A peptide which is a human homologue of guinea pig eotaxin or a novel chemokine, in particular, a human CC chemokine having an activity on human eosinocytes; the structural gene of the peptide; an expression vector having the gene; a transformant having the expression vector introduced thereinto; a process for producing the peptide by using the transformant; a monoclonal antibody against the peptide; a method for assaying the peptide by using the monoclonal antibody; and a method for screening an agonist or antagonist of the peptide.

JP2023509708	ANTI-TCR ANTIBODY MOLECULES AND USES THEREOF
JP2002502591	[Title of Invention] Neokine protein and nucleic acid molecule and their uses.
JPS6069020	FRAME GROWTH FACTOR

KITAURA MOTOJI (JP)
NAKAJIMA TOSHIHIRO (JP)
HARADA SHIGENORI (JP)

PCT/JP1996/002851

April 10, 1997

October 01, 1996

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SHIONOGI & CO (JP)
KITAURA MOTOJI (JP)
NAKAJIMA TOSHIHIRO (JP)
HARADA SHIGENORI (JP)

C07K14/52; C07K16/24; C12N15/19; A61K38/00; (IPC1-7): C07K14/52; C07K16/24; C12N5/10; C12N15/19; C12P21/02; C12P21/08; G01N33/53

J. BIOL. CHEM., Vol. 271, No. 13, March 1996, M. KITAURA et al., "Molecular Cloning of Human Eotaxin, ...CC Chemokine Receptor 3", p. 7725-7730.
BIOCHEM. BIOPHYS. RES. COMMUN., Vol. 225, Aug. 1996, J. BARTELS et al., "Human Dermal Fibroblasts Express Eotaxin ...", p. 1045-1051.
J. CLIN. INVEST., Vol. 97, No. 3, Feb. 1996, P.D. PONATH et al., "Cloning of the Human Eosinophil Chemoattractant, Eotaxin", p. 604-612.
BIOCHEM. BIOPHYS. RES. COMMUN., Vol. 205, 1994, P.J. JOSE et al., "Eotaxin: Cloning of an Eosinophil Chemoattractant ...", p. 788-794.

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