Title:
NOVEL IMIDAZOLE DERIVATIVE, PHARMACEUTICAL USE THEREOF, AND INTERMEDIATE THEREFOR
Document Type and Number:
WIPO Patent Application WO/1993/020065
Kind Code:
A1
Abstract:
An imidazole derivative represented by general formula (I), wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof. A process for producing the derivative or salt, and a pharmaceutical use thereof, in particular, a prophylactic and/or therapeutic agent for diseases induced by thromboxane A2 or histamine. A compound represented by genenral formula (II) or (IV), wherein each symbol is as defined in the specification. The imidazole derivative and the salt are useful as a prophylactic and/or therapeutic agent for diseases induced by thromboxane A2 or histamine, and the compounds (II) and (IV) are novel.
Inventors:
MATSUI HIROSHI (JP)
KAMIYA SHOJI (JP)
SHIRAHASE HIROAKI (JP)
NAKAMURA SHOHEI (JP)
KAMIYA SHOJI (JP)
SHIRAHASE HIROAKI (JP)
NAKAMURA SHOHEI (JP)
Application Number:
PCT/JP1993/000378
Publication Date:
October 14, 1993
Filing Date:
March 26, 1993
Export Citation:
Assignee:
KYOTO PHARMA IND (JP)
MATSUI HIROSHI (JP)
KAMIYA SHOJI (JP)
SHIRAHASE HIROAKI (JP)
NAKAMURA SHOHEI (JP)
MATSUI HIROSHI (JP)
KAMIYA SHOJI (JP)
SHIRAHASE HIROAKI (JP)
NAKAMURA SHOHEI (JP)
International Classes:
C07D521/00; (IPC1-7): C07D401/14; A61K31/415; A61K31/445; A61K31/495; C07D403/04; C07D403/06
Foreign References:
| JPH037281A | 1991-01-14 | |||
| JPS5841875A | 1983-03-11 | |||
| JPS5697267A | 1981-08-05 | |||
| JPS55133380A | 1980-10-17 | |||
| JPS54132569A | 1979-10-15 |
Other References:
See also references of EP 0597112A4
Download PDF: