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Title:
NOVEL LACTOBACILLUS PLANTARUM PROBIO 88, EXTRACT THEREOF, AND COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2023/048334
Kind Code:
A1
Abstract:
The present invention provides a Lactobacillus plantarum) Probio 88 strain and an extract and a composition, each containing same. The strain, extract, and composition according to the present invention have the effects of suppressing SARS-CoV-2 infection and replication, reducing the intracellular accumulation of inflammation and reactive oxygen species (ROS), decreasing extracellular signal-regulated kinase (ERK) activity, enhancing antiviral activity, and being able to be advantageously used as a therapeutic agent or adjuvant for coronaviral diseases.

Inventors:
PARK YONG-HA (KR)
LEW LEE CHING (KR)
HOR YAN YAN (KR)
Application Number:
PCT/KR2021/017005
Publication Date:
March 30, 2023
Filing Date:
November 18, 2021
Export Citation:
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Assignee:
PROBIONIC INC (KR)
International Classes:
C12N1/20; A23K10/16; A23L33/135; A61K8/99; A61K35/742; A61P31/14; A61Q19/00; C12R1/25
Foreign References:
KR20150044764A2015-04-27
KR20200007742A2020-01-22
KR20160047125A2016-05-02
KR20180033912A2018-04-04
Other References:
RATHER IRFAN A., CHOI SY-BING, KAMLI MAJID RASOOL, HAKEEM KHALID REHMAN, SABIR JAMAL S. M., PARK YONG-HA, HOR YAN-YAN: "Potential Adjuvant Therapeutic Effect of Lactobacillus plantarum Probio-88 Postbiotics against SARS-COV-2", VACCINES, vol. 9, no. 10, pages 1067, XP093053525, DOI: 10.3390/vaccines9101067
Attorney, Agent or Firm:
KIM, Youngrok (KR)
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