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Title:
NOVEL METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATE
Document Type and Number:
WIPO Patent Application WO/2019/044946
Kind Code:
A1
Abstract:
A method for producing a compound represented by formula (C), the method comprising a step for converting a compound represented by formula (B) (wherein R1 represents an amino group protected by a protecting group) by intramolecular cyclization into a compound represented by formula (C) (wherein R1 is defined as above).

Inventors:
NISHI YOSHIO (JP)
SAKANISHI KOHEI (JP)
NOGUCHI SHIGERU (JP)
TAKEDA TADAHIRO (JP)
Application Number:
PCT/JP2018/032055
Publication Date:
March 07, 2019
Filing Date:
August 30, 2018
Export Citation:
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Assignee:
DAIICHI SANKYO CO LTD (JP)
International Classes:
C07C231/12; A61K31/4745; A61K39/395; A61K47/68; A61P35/00; C07C233/15; C07C233/33; C07C233/54; C07D491/22; C07K7/06; C07K16/00; C07K16/28; C07B61/00
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See also references of EP 3677568A4
Attorney, Agent or Firm:
ISHIBASHI Koki et al. (JP)
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