Title:
NOVEL METHODS FOR THE PREPARATION OF 4-[4-(4-METHOXYMETHOXY-4'-METHYL-BIPHENYL-2-YL)-BUT-3-ENE-(E)-1-YNYL]-BENZOIC ACID
Document Type and Number:
WIPO Patent Application WO2005037756
Kind Code:
A3
Abstract:
The invention relates to novel methods for the preparation of 4-[4-(4-methoxymethoxy-4'-methyl-biphenyl-2-yl)-but-3-ene (E)-1-ynyl]-benzoic acid.
Inventors:
MOUREOU CHRISTINE (FR)
MULLER FRANCK (FR)
BIADATTI THIBAUD (FR)
PASCAL JEAN-CLAUDE (FR)
MULLER FRANCK (FR)
BIADATTI THIBAUD (FR)
PASCAL JEAN-CLAUDE (FR)
Application Number:
PCT/EP2004/013741
Publication Date:
September 15, 2005
Filing Date:
September 09, 2004
Export Citation:
Assignee:
GALDERMA RES & DEV (FR)
MOUREOU CHRISTINE (FR)
MULLER FRANCK (FR)
BIADATTI THIBAUD (FR)
PASCAL JEAN-CLAUDE (FR)
MOUREOU CHRISTINE (FR)
MULLER FRANCK (FR)
BIADATTI THIBAUD (FR)
PASCAL JEAN-CLAUDE (FR)
International Classes:
C07C41/48; C07C41/50; C07C43/313; C07C45/68; C07C45/71; C07C47/57; C07C47/575; C07C51/09; (IPC1-7): C07C41/50; C07C45/68; C07C51/347; C07C51/353
Foreign References:
| EP0879814A1 | 1998-11-25 |
Other References:
T.W. GREENE, P.G.M. WUTS: "Protective groups in organic synthesis third edition", 1999, JOHN WILEY & SONS, INC., ISSN: 0-471-22057-4, XP002279148
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002279149, Database accession no. 6089538
G.R. BROWN ET AL: "Synthesis and activity of a novel series of 3-biarylquinuclidine squalene synthase inhibitors", J.MED.CHEM., vol. 39, no. 15, 1996, pages 2971 - 2979, XP002279146
Y. OHSHIRO ET AL: "Reduction of gem-dibomides with diethyl phosphite", J.ORG.CHEM., vol. 46, no. 18, 1981, pages 3745 - 3747, XP002279147
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002279149, Database accession no. 6089538
G.R. BROWN ET AL: "Synthesis and activity of a novel series of 3-biarylquinuclidine squalene synthase inhibitors", J.MED.CHEM., vol. 39, no. 15, 1996, pages 2971 - 2979, XP002279146
Y. OHSHIRO ET AL: "Reduction of gem-dibomides with diethyl phosphite", J.ORG.CHEM., vol. 46, no. 18, 1981, pages 3745 - 3747, XP002279147
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