Title:
NOVEL MUCIN GLYCOPROTEIN AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2007/020889
Kind Code:
A1
Abstract:
Disclosed is a novel mucin glycoprotein. Also disclosed is a method for production of the mucin glycoprotein. A mucin glycoprotein having a repeated structure having 3 to 2000 of repeating units, each of the repeating units comprising an amino acid sequence represented by the formula I: Val-Xaa-Glu-Thr-Thr-Ala-Ala-Pro (wherein Xaa represents Val or Ile), and also having a sugar chain composed of one or more monosaccharides attached on at least one amino acid residue in the structure; a composition comprising the novel mucin glycoprotein; and a molecular weight marker comprising the novel mucin glycoprotein.
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Inventors:
USHIDA KIMINORI (JP)
MASUDA AKIKO (JP)
DOHMAE NAOSHI (JP)
FURUKAWA HIDEMITSU (JP)
MIYAWAKI ATSUSHI (JP)
MASUDA AKIKO (JP)
DOHMAE NAOSHI (JP)
FURUKAWA HIDEMITSU (JP)
MIYAWAKI ATSUSHI (JP)
Application Number:
PCT/JP2006/315939
Publication Date:
February 22, 2007
Filing Date:
August 11, 2006
Export Citation:
Assignee:
RIKEN (JP)
USHIDA KIMINORI (JP)
MASUDA AKIKO (JP)
DOHMAE NAOSHI (JP)
FURUKAWA HIDEMITSU (JP)
MIYAWAKI ATSUSHI (JP)
USHIDA KIMINORI (JP)
MASUDA AKIKO (JP)
DOHMAE NAOSHI (JP)
FURUKAWA HIDEMITSU (JP)
MIYAWAKI ATSUSHI (JP)
International Classes:
A23L1/305; C07K14/435; A61K38/00; A61P3/00; A61P17/16; A61P31/04; A61P43/00; C07K1/113; C07K1/14; C12P21/02; C07K7/06
Domestic Patent References:
| WO1995017428A1 | 1995-06-29 | |||
| WO1999063964A1 | 1999-12-16 |
Foreign References:
| JP2004099513A | 2004-04-02 | |||
| JP2003321497A | 2003-11-11 | |||
| JP2001178492A | 2001-07-03 | |||
| JP2002370991A | 2002-12-24 | |||
| JP2002143824A | 2002-05-21 | |||
| JPH06217737A | 1994-08-09 |
Other References:
GUYONNET DUPERAT V. ET AL.: "Characterization of the human mucin gene MUC5AC: a consensus cysteine-rich domain for 11p15 mucin genes?", BIOCHEM. J., vol. 305, 1995, pages 211 - 219, XP001107195
BEDELL J.A. ET AL.: "Sorghum Genome Sequencing by Methylation Filtration", PLOS BIOLOGY, vol. 3, no. 1, January 2005 (2005-01-01), pages E13, XP003003845
OTA T. ET AL.: "Complete sequencing and characterization of 21,243 full-length human cDNAs", NAT. GENET., vol. 36, no. 1, 2004, pages 40 - 45, XP008055982
CALDWELL R.B. ET AL.: "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis", GENOME BIOLOGY, vol. 6, no. 1, 2004, pages R6, XP021012938
V. SCHMIDT; A. BALLY; K. BECK; M. HALLER; W. K. SCHLAGE; C. WEBER: "The extracellular matrix (mesoglea) of hydrozoan jellyfish and its ability to support cell adhesion and spreading", HYDROBIOLOGIA, vol. 216-217, 1997, pages 3 - 10
"Emergence and Distribution", vol. VII, 2003, KOUSEISHA KOUSEIKAKU CO., LTD., article "Marine UFO Jellyfish", pages: 41 - 77
DUCKLOW ET AL., LIMNOLOGY AND OCEANOGRAPHY, vol. 24, no. 4, 1979, pages 706 - 714
BEDELL J.A. ET AL.: "Sorghum Genome Sequencing by Methylation Filtration", PLOS BIOLOGY, vol. 3, no. 1, January 2005 (2005-01-01), pages E13, XP003003845
OTA T. ET AL.: "Complete sequencing and characterization of 21,243 full-length human cDNAs", NAT. GENET., vol. 36, no. 1, 2004, pages 40 - 45, XP008055982
CALDWELL R.B. ET AL.: "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis", GENOME BIOLOGY, vol. 6, no. 1, 2004, pages R6, XP021012938
V. SCHMIDT; A. BALLY; K. BECK; M. HALLER; W. K. SCHLAGE; C. WEBER: "The extracellular matrix (mesoglea) of hydrozoan jellyfish and its ability to support cell adhesion and spreading", HYDROBIOLOGIA, vol. 216-217, 1997, pages 3 - 10
"Emergence and Distribution", vol. VII, 2003, KOUSEISHA KOUSEIKAKU CO., LTD., article "Marine UFO Jellyfish", pages: 41 - 77
DUCKLOW ET AL., LIMNOLOGY AND OCEANOGRAPHY, vol. 24, no. 4, 1979, pages 706 - 714
Attorney, Agent or Firm:
HIRAKI, Yusuke et al. (Toranomon 4-chome Minato-ku, Tokyo 01, JP)
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