Title:
NOVEL OLEFIN DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2013/035827
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide: a novel compound which is represented by formula (I') and has ACC2 inhibitory activity; and a medicinal composition which contains the compound. (In the formula, R1 represents a substituted or unsubstituted aryl group or the like; X1 represents -O- or the like; R2 represents a hydrogen atom or the like; R3 represents a hydrogen atom or the like; n represents an integer of 0-3; ring A represents an aromatic carbon ring or the like; R9 represents a substituted or unsubstituted alkyl group or the like; m represents an integer of 0-4; each of R4 and R5 represents a hydrogen atom or the like; R6 represents a substituted or unsubstituted alkyl group or the like; R13 represents a hydrogen atom or the like; X5 represents a single bond or the like; R7 represents a hydrogen atom or the like; and R8 represents a substituted or unsubstituted alkylcarbonyl group or the like.)
Inventors:
MATSUMURA AKIRA (JP)
KOBAYASHI NAOTAKE (JP)
NISHIURA YUJI (JP)
TAGASHIRA SACHIE (JP)
KIDA SHIRO (JP)
WATANABE KANA (JP)
YONEHARA MITSUHIRO (JP)
KOBAYASHI NAOTAKE (JP)
NISHIURA YUJI (JP)
TAGASHIRA SACHIE (JP)
KIDA SHIRO (JP)
WATANABE KANA (JP)
YONEHARA MITSUHIRO (JP)
Application Number:
PCT/JP2012/072859
Publication Date:
March 14, 2013
Filing Date:
September 07, 2012
Export Citation:
Assignee:
SHIONOGI & CO (JP)
MATSUMURA AKIRA (JP)
KOBAYASHI NAOTAKE (JP)
NISHIURA YUJI (JP)
TAGASHIRA SACHIE (JP)
KIDA SHIRO (JP)
WATANABE KANA (JP)
YONEHARA MITSUHIRO (JP)
MATSUMURA AKIRA (JP)
KOBAYASHI NAOTAKE (JP)
NISHIURA YUJI (JP)
TAGASHIRA SACHIE (JP)
KIDA SHIRO (JP)
WATANABE KANA (JP)
YONEHARA MITSUHIRO (JP)
International Classes:
A61K31/165; C07D213/64; A61K31/415; A61K31/422; A61K31/426; A61K31/427; A61K31/44; A61K31/4439; A61K31/444; A61K31/4545; A61K31/496; A61K31/4985; A61K31/50; A61K31/505; A61K31/5377; A61P3/04; A61P3/10; A61P43/00; C07C233/05; C07D213/65; C07D231/12; C07D237/14; C07D239/34; C07D277/20; C07D277/34; C07D401/12; C07D405/12; C07D413/12; C07D417/04; C07D417/12; C07D417/14; C07D487/04
Domestic Patent References:
| WO2008079610A2 | 2008-07-03 | |||
| WO2010003624A2 | 2010-01-14 | |||
| WO1995030671A1 | 1995-11-16 | |||
| WO1993002037A1 | 1993-02-04 |
Other References:
WOOLLARD, P. M. ET AL.: "Use of high-performance liquid chromatography-thermospray mass spectrometry and gas chromatography-electron- impact mass spectrometry in the identification of the metabolites of a-methylacetohydroxamic acids, potential anti-asthmatic agents", JOURNAL OF CHROMATOGRAPHY, BIOMEDICAL APPLICATIONS, vol. 562, no. 1-2, 1991, pages 249 - 256, XP026508221, DOI: doi:10.1016/0378-4347(91)80582-W
Attorney, Agent or Firm:
TAKAYAMA, Hirotsugu et al. (JP)
Hiromitsu Takayama (JP)
Hiromitsu Takayama (JP)
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